Listar por autoría "f60c9b18-455c-4498-b139-8bb0f9bcdb27"
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c-Fos immunoreactivity in prefrontal, basal ganglia and limbic areas of the rat brain after central and peripheral administration of ethanol and its metabolite acetaldehyde
Segovia, Kristen N.; Vontell, Regina; López Cruz, Laura; Salamone, John; Correa, Merce Frontiers (2013)Considerable evidence indicates that the metabolite of ethanol (EtOH), acetaldehyde, is biologically active. Acetaldehyde can be formed from EtOH peripherally mainly by alcohol dehydrogenase (ADH), and also centrally by ... -
Changes in nucleus accumbens and neostriatal c-Fos and DARPP-32 immunoreactivity during different stages of food-reinforced instrumental training
Segovia, Kristen N.; Correa, Merce; Lennington, Jessica B.; Conover, Joanne C.; Salamone, John Blackwells Publishing (2012)Nucleus accumbens is involved in several aspects of instrumental behavior, motivation and learning. Recent studies showed that dopamine (DA) release in the accumbens shell was significantly increased on the first day of ... -
Nucleus accumbens and effort-related functions: behavioral and neural markers of the interactions between adenosine A2A and dopamine D2 receptors
Farrar, Andrew M.; Segovia, Kristen N.; Randall, Patrick A.; Nunes, Eric J.; Collins, Lyndsey E.; Stopper, Colin M.; Port, Russell G.; Hockemeyer, J.; Müller, Christa E.; Correa, Merce; Salamone, John Elsevier (2010-04)Nucleus accumbens dopamine (DA) is a critical component of the brain circuitry regulating work output in reinforcement-seeking behavior and effort-related choice behavior. Moreover, there is evidence of an interaction ... -
Piecing together the puzzle of acetaldehyde as a neuroactive agent
Correa, Merce; Salamone, John; Segovia, Kristen N.; Pardo Andrés, Marta; Longoni, Rosanna; Spina, Liliana; PEANA, Alessandra Tiziana; Vinci, Stefania; Acquas, Elio Elsevier (2012-01)Mainly known for its more famous parent compound, ethanol, acetaldehyde was first studied in the 1940s, but then research interest in this compound waned. However, in the last two decades, research on acetaldehyde has seen ... -
Potential anxiogenic effects of cannabinoid CB1 receptor antagonists/inverse agonists in rats: Comparisons between AM4113, AM251, and the benzodiazepine inverse agonist FG-7142
Sink, Kelly S.; Segovia, Kristen N.; Sink, J.; Randall, Patrick A.; Collins, Lyndsey E.; Correa, Merce; Markus, E. J.; Vemuri, Venkata Kiran; Makriyannis, Alexandros; Salamone, John Elsevier (2010)Cannabinoid CB1 inverse agonists suppress food-motivated behaviors, but may also induce psychiatric effects such as depression and anxiety. To evaluate behaviors potentially related to anxiety, the present experiments ... -
Slow phasic changes in nucleus accumbens dopamine release during fixed ratio acquisition: a microdialysis study
Segovia, Kristen N.; Correa, Merce; Salamone, John Elsevier (2011)Nucleus accumbens dopamine (DA) is a critical component of the brain circuitry regulating behavioral output during reinforcement-seeking behavior. Several studies have investigated the characteristics of accumbens DA release ...