Listar por autoría "efede73a-5076-4e00-93fc-6f41503787f1"
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Acetate as an active metabolite of ethanol: studies of locomotion, loss of righting reflex, and anxiety in rodents
Pardo Andrés, Marta; Betz, Adrienne J.; San Miguel Segura, Noemí; López Cruz, Laura; Salamone, John; Correa, Merce Frontiers (2013)It has been postulated that a number of the central effects of ethanol are mediated via ethanol metabolites: acetaldehyde and acetate. Ethanol is known to produce a large variety of behavioral actions such anxiolysis, ... -
Activational and effort-related aspects of motivation: neural mechanisms and implications for psychopathology
Salamone, John; Yohn, Samantha E.; López Cruz, Laura; San Miguel Segura, Noemí; Correa, Merce Oxford University Press (2016-04-26)Motivation has been defined as the process that allows organisms to regulate their internal and external environment, and control the probability, proximity and availability of stimuli. As such, motivation is a complex ... -
Caffeine Modulates Food Intake Depending on the Context That Gives Access to Food: Comparison With Dopamine Depletion
Correa, Merce; San Miguel Segura, Noemí; López Cruz, Laura; Carratalá-Ros, Carla; Olivares-García, Régulo; Salamone, John (2018-09-06)Caffeine is a methylxanthine consumed in different context s to potentiate alertness and reduce fatigue. However, caffeine can induce anxiety at hig h doses. Caffeine is also a minor psychostimulant that seems to act ... -
Caffeine modulates voluntary alcohol intake in mice depending on theaccess conditions: Involvement of adenosine receptors and the role of individual differences
San Miguel Segura, Noemí; López Cruz, Laura; Müller, Christa E.; Salomone, John D.; Correa, Merce Elsevier (2019)Caffeine is the most consumed psychoactive stimulant and the main active ingredient of energy drinks.Epidemiology studies have shown a positive correlation between the consumption of energy drinks and that ofethanol. The ... -
Choosing voluntary exercise over sucrose consumption depends upon dopamine transmission: effects of haloperidol in wild type and adenosine A2AKO mice
Correa, Merce; Pardo Andrés, Marta; Bayarri Iturralde, Pilar; López Cruz, Laura; San Miguel Segura, Noemí; Valverde, Olga; LEDENT, Catherine; Salamone, John Springer (2016-02)Rationale: Mesolimbic dopamine (DA) regulates behavioral activation and effort-related decision-making in motivated behaviors. Mesolimbic DA D2 receptors are co-localized with adenosine A2A receptors, and they interact in ... -
Dosis medias y altas de cafeína no revierten la incoordinación motora producida por alcohol en ratones
San Miguel Segura, Noemí; López Cruz, Laura; Pardo Andrés, Marta; Correa, Merce Universitat Jaume I (2015)En los últimos años, el consumo de las bebidas energéticas ha incrementado notablemente, así como su concentración de cafeína. Con frecuencia, estas bebidas se consumen junto a grandes cantidades de alcohol con el objetivo ... -
Effort-related motivational effects of the pro-inflammatory cytokine interleukin-6: pharmacological and neurochemical characterization
Yohn, Samantha E.; Arif, Yumna; Haley, Allison; Tripodi, Guiseppe; Baqi, Younis; Müller, Christa E.; San Miguel Segura, Noemí; Correa, Merce; Salamone, John Springer Verlag (2016)Rationale Motivational dysfunctions such as anergia, fatigue, and reduced effort expenditure are common in patients with depression and other disorders. Pro-inflammatory cytokines are implicated in depression, and ... -
El ejercicio forzado previene la anergia inducida por la depleción de dopamina. Estudios comparando la selección entre actividad física o la ingesta de alimentos dulces
Bayarri Iturralde, Pilar; Ros, Xavier; López Cruz, Laura; San Miguel Segura, Noemí; Monferrer Sales, Lidón; Correa, Merce Universitat Jaume I (2015)Disfunciones relacionadas con el esfuerzo como la anergia y la fatiga son síntomas centrales de la depresión y otros trastornos. El sistema dopaminérgico (DA) mesolímbico desempeña un papel crítico en la activación de ... -
Elegir entre consumir dulces o hacer ejercicio depende de la modulación dopaminérgica en el circuito cerebral que regula la motivación
Pardo Andrés, Marta; Bayarri Iturralde, Pilar; López Cruz, Laura; San Miguel Segura, Noemí; Correa, Merce Universitat Jaume I (2015)Introducción: Los organismos continuamente toman decisiones basadas en el valor de los reforzadores y los costes que suponen las respuestas para conseguirlos. La magnitud del esfuerzo que la conducta a ejecutar requiere, ... -
Ethanol and Caffeine Effects on Social Interaction and Recognition in Mice: Involvement of Adenosine A(2A) and A(1) Receptors
López Cruz, Laura; San Miguel Segura, Noemí; Bayarri Iturralde, Pilar; Baqi, Younis; Müller, Christa E.; Salomone, John D.; Correa, Merce Frontiers Media (2016-11)Ethanol and caffeine are frequently consumed in combination and have opposite effects on the adenosine system: ethanol metabolism leads to an increase in adenosine levels, while caffeine is a non-selective adenosine ... -
Interacción entre receptores d2 y a2a. Toma de decisiones basada en el esfuerzo mediante un Programa de Razón Progresiva en ratas
Bayarri Iturralde, Pilar; López Cruz, Laura; San Miguel Segura, Noemí; Monferrer Sales, Lidón; Correa, Merce Universitat Jaume I (2015)Uno de los síntomas motivacionales característicos de la depresión y que supone un mayor problema para la realización de tareas cotidianas, es la anergia. Este síntoma supone una disminución del vigor y el esfuerzo que ... -
Preference for Exercise vs. More Sedentary Reinforcers: Validation of an Animal Model of Tetrabenazine-Induced Anergia
Carratalá-Ros, Carla; López Cruz, Laura; San Miguel Segura, Noemí; Ibáñez-Marín, Patricia; Martínez Verdú, Andrea; Salamone, John; Correa, Merce Frontiers Media (2020-01-30)Physical activities can have intrinsic motivational or reinforcing properties. The choice to engage in voluntary physical activity is undertaken in relation to the selection of other alternatives, such as sedentary ... -
La reducción de los niveles de dopamina no altera la conducta de «atracón de comida» en ratones, pero la cafeína modula el consumo en función de los niveles de ansiedad.
Olivares-García, Régulo; San Miguel Segura, Noemí; Pérez García, José Manuel; Camañes Martorell, Joan; Correa, Merce Universitat Jaume I (2016)Introducción: La conducta de «atracón» consiste en consumir, en un período breve de tiempo, más cantidad de alimentos del que se consumiría normalmente en situaciones similares y en un plazo de tiempo igual. Es una ... -
Selection of sucrose concentration depends on the effort required to obtain it: studies using tetrabenazine, D1, D2, and D3 receptor antagonists
Pardo Andrés, Marta; López Cruz, Laura; San Miguel Segura, Noemí; Salamone, John; Correa, Merce Springer Verlag (2015)Rationale Low doses of dopamine (DA) antagonists and accumbens DA depletions reduce food-reinforced instrumental behavior but do not impair primary food motivation, causing animals to reallocate behavior away from ... -
The pharmacology of effort-related choice behavior: Dopamine, depression, and individual differences
Salamone, John; Correa, Merce; Yohn, Samantha E.; López Cruz, Laura; San Miguel Segura, Noemí; Alatorre, Luisa Elsevier (2016)This review paper is focused upon the involvement of mesolimbic dopamine (DA) and related brain systems in effort-based processes. Interference with DA transmission affects instrumental behavior in a manner that interacts ...