Listar por autoría "da468d5f-efc1-4f28-830a-9a476f79871a"

Mostrando ítems 1-4 de 4

    • openAccess   Association between several immune response-related genes and the effectiveness of biological treatments in patients with moderate-to-severe psoriasis 

      Loras Monfort, Alba; Gil-Barrachina, Marta; Hernando, Barbara; Pérez-Pastor, Gemma María; Martinez-Domenech, Alvaro; Mahiques, Laura; PITARCH BORT, GERARD; Valcuende-Cavero, Francisca; Ballester, Rosa; Marques-Torrejon, Maria Angeles; Martinez-Cadenas, Conrado Wiley (2024-01-04)
      Biological therapies are safer and more effective against psoriasis than conventional treatments. Even so, 30–50% of psoriatic patients show an inadequate response, which is associated with individual genetic heterogeneity. ...

    • openAccess   Lrig1 regulates the balance between proliferation and quiescence in glioblastoma stem cells 

      Ferguson, Kirsty; Blin, Carla; Alfazema, Neza; Gangoso, Ester; Pollard, Steven; Marques-Torrejon, Maria Angeles Frontiers Media (2022)
      Patients with glioblastoma (GBM) face a dismal prognosis. GBMs are driven by glioblastoma stem cells (GSCs) that display a neural stem cell (NSC)-like phenotype. These glioblastoma stem cells are often in a quiescent state ...

    • openAccess   Neural Stem Cells as Potential Glioblastoma Cells of Origin 

      Loras Monfort, Alba; Gonzalez Bonet, Luis Germán; Gutierrez-Arroyo, Julia L.; Martinez-Cadenas, Conrado; Marques-Torrejon, Maria Angeles MDPI (2023)
      Glioblastoma multiforme (GBM) is the most malignant brain tumor in adults and it remains incurable. These tumors are very heterogeneous, resistant to cytotoxic therapies, and they show high rates of invasiveness. Therefore, ...

    • openAccess   UV-Induced Somatic Mutations Driving Clonal Evolution in Healthy Skin, Nevus, and Cutaneous Melanoma 

      Loras Monfort, Alba; Gil-Barrachina, Marta; Marques-Torrejon, Maria Angeles; Pérez-Pastor, Gemma María; Martinez-Cadenas, Conrado MDPI (2022-08-29)
      Introduction: Due to its aggressiveness, cutaneous melanoma (CM) is responsible for most skin cancer-related deaths worldwide. The origin of CM is closely linked to the appearance of UV-induced somatic mutations in ...