Listar por autoría "cfd26788-4a84-4724-81bc-bd3a7050d00f"
Mostrando ítems 1-4 de 4
-
Combined Theoretical and Experimental Study to Unravel the Differences in Promiscuous Amidase Activity of Two Nonhomologous Enzymes
Galmés, Miquel À; Nödling, Alexander; Luk, Louis Y. P.; Świderek, Katarzyna; Moliner, Vicent American Chemical Society (2021-07-16)Convergent evolution has resulted in nonhomologous enzymes that contain similar active sites that catalyze the same primary and secondary reactions. Comparing how these enzymes achieve their reaction promiscuity can yield ... -
Computational Studies Suggest Promiscuous Candida antarctica Lipase B as an Environmentally Friendly Alternative for the Production of Epoxides
Galmés, Miquel À; Świderek, Katarzyna; Moliner, Vicent American Chemical Society (2021-07-26)Environmentally friendly processes are nowadays a trending topic to get highly desired chemical compounds and, in this sense, the use of enzyme-catalyzed routes is becoming a promising alternative to traditional synthetic ... -
Exploring the Origin of Amidase Substrate Promiscuity in CALB by a Computational Approach
Galmés, Miquel À; García-Junceda, Eduardo; Świderek, Katarzyna; Moliner, Vicent American Chemical Society (2020)Enzyme promiscuity attracts the interest of the industrial and academic sectors because of its application in the design of biocatalysts. The amidase activity of Candida antarctica lipase B (CALB) on two different substrates ... -
Mechanistic studies of a lipase unveil effect of pH on hydrolysis products of small PET modules
Świderek, Katarzyna; Velasco-Lozano, Susana; Galmés, Miquel À; Olazabal, Ion; Sardon, Haritz; López Gallego, Fernando; Moliner, Vicent Springer Nature (2023-06-15)Biocatalysis is a key technology enabling plastic recycling. However, despite advances done in the development of plastic-degrading enzymes, the molecular mechanisms that govern their catalytic performance are poorly ...