Listar por autoría "b192c07f-45d0-40d6-9edb-ebb800fdaba4"

Mostrando ítems 1-20 de 22

    • openAccess   A possible use of melatonin in the dental field: Protein adsorption andinvitrocell response on coated titanium 

      Cerqueira, Andreia; Romero-Gavilán, Francisco J; Araújo-Gomes, Nuno; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Elsevier (2020)
      Melatonin (MLT) is widely known for regulating the circadian cycles and has been studied for its role in boneregeneration and inflammation. Its application as a coating for dental implants can condition the local ...

    • closedAccess   A single coating with antibacterial properties for prevention of medical device-associated infections 

      García-Arnáez, Iñaki; Palla, B.; Suay, Julio; Romero-Gavilán, Francisco J; García Fernández, Luis Amable; Fernández Gutiérrez, Mar; Goñi, Isabel; GURRUCHAGA, MARILO Elsevier (2019-04)
      Human bacterial pathogens found on medical implants are one of the main causes of morbidity and mortality, making the development of novel coatings the primary strategy in the prevention of medical device-associated ...

    • openAccess   Antibacterial and osteogenic ­Cu-­doped sol-­gel coatings for Ti implant functionalization 

      Romero-Gavilán, Francisco J; Arias-Mainer, Carlos; Cerqueira, Andreia; García-Arnáez, Iñaki; Scalschi, Loredana; Vicedo, Begonya; Azkargorta, Mikel; Elortza, Felix; Gurruchaga, Mariló; Goñi, Isabel; Suay, Julio Wiley (2023)

    • openAccess   Bioactive potential of silica coatings and its effect on the adhesion of proteins to titanium implants 

      Romero-Gavilán, Francisco J; Gomes, Nuno; Sánchez-Pérez, Ana María; García-Arnáez, Iñaki; Elortza, Felix; Azkargorta, Mikel; Martín de Llano, J.J.; Carda, C.; Gurruchaga, Marilo; Suay, Julio; Goñi, Isabel Elsevier (2018-02-01)
      There is an ever-increasing need to develop dental implants with ideal characteristics to achieve specific and desired biological response in the scope of improve the healing process post-implantation. Following that ...

    • openAccess   Bioactive zinc-doped sol-gel coating modulates protein adsorption patterns and in vitro cell responses 

      Cerqueira, Andreia; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Iloro, Ibon; Azkargorta, Mikel; Elortza, Felix; Izquierdo Escrig, Raul; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Elsevier (2020-12-30)
      Zinc is an essential element with an important role in stimulating the osteogenesis and mineralization and suppressing osteoclast differentiation. In this study, new bioactive ZnCl2-doped sol-gel materials were designed ...

    • openAccess   Characterization of magnesium doped sol-gel biomaterial for bone tissue regeneration: The effect of Mg ion in protein adsorption 

      Cerqueira, Andreia; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Izquierdo Escrig, Raul; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Elsevier (2021-06-01)
      Magnesium is the fourth most abundant element in the human body with a wide battery of functions in the maintenance of normal cell homeostasis. In the bone, this element incorporates in the hydroxyapatite structure and it ...

    • openAccess   Complex effects of Mg-biomaterials on the osteoblast cell machinery: A proteomic study 

      Cerqueira, Andreia; García-Arnáez, Iñaki; Romero-Gavilán, Francisco J; Azkargorta, Mikel; Elortza, Felix; Martín de Llanos, José Javier; Carda, Carmen; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Elsevier (2022)
      The cell–biomaterial interface is highly complex; thousands of molecules and many processes participate in its formation. Growing demand for improved biomaterials has highlighted the need to understand the structure and ...

    • openAccess   Correlation between biological responses in vitro and in vivo to Ca-doped sol-gel coatings assessed using proteomic analysis 

      García-Arnáez, Iñaki; Romero-Gavilán, Francisco J; Cerqueira, Andreia; Elortza, Felix; Azkargorta, Mikel; Muñoz Guzón, Fernando; Mata Roig, Manuel; MARTIN DE LLANO, JOSE JAVIER; Suay, Julio; GURRUCHAGA, MARILO; Goñi, Isabel Elsevier (2022-10-21)
      Poor correlation between the results of in vitro testing and the subsequent in vivo experiments hinders the design of biomaterials. Thus, new characterisation methods are needed. This study used proteomic and histological ...

    • openAccess   Development and characterisation of strontium-doped sol-gel coatings to optimise the initial bone regeneration processes 

      García-Arnáez, Iñaki; Cerqueira, Andreia; Romero-Gavilán, Francisco J; Elortza, Felix; Azkargorta, Mikel; Iloro, Ibon; Suay, Julio; Goñi, Isabel; GURRUCHAGA, MARILO Elsevier (2022)
      Strontium plays an important role in bone regeneration; it promotes the differentiation and maturation of osteoblasts and inhibits the activity of osteoclasts. Our principal objective in this study was to formulate new ...

    • openAccess   Influence of calcium ion-modified implant surfaces in protein adsorption and implant integration 

      Anitua, Eduardo; Cerqueira, Andreia; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Azkagorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio; Tejero, Ricardo Springer (2021-04-21)
      Calcium (Ca) is a well-known element in bone metabolism and blood coagulation. Here, we investigate the link between the protein adsorption pattern and the in vivo responses of surfaces modified with calcium ions (Ca-ion) ...

    • openAccess   Insight into the antibacterial mechanism of Cu-enriched sol–gel coatings employing proteomics 

      Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Cerqueira, Andreia; Scalschi, Loredana; Vicedo, Begonya; Villagrasa, Alejandro; Izquierdo, Raúl; Elortza, Felix; Gurruchaga, Mariló; Goñi, Isabel; Suay, Julio Royal Society of Chemistry (2023)
      Advanced antibacterial biomaterials can help reduce the severe consequences of infections. Using copper compounds is an excellent option to achieve this goal; they offer a combination of regenerative and antimicrobial ...

    • openAccess   Osseointegration mechanisms: a proteomic approach 

      Gomes, Nuno; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Sánchez-Pérez, Ana María; Azkargorta, Mikel; Elortza, Felix; Martín de Llano, J.J.; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Springer-Verlag (2018-03)
      The prime objectives in the development of biomaterials for dental applications are to improve the quality of osseointegration and to short the time needed to achieve it. Design of implants nowadays involves changes in ...

    • openAccess   Osteointegración de implantes de titanio con superficies activas. Un estudio proteómico 

      Romero-Gavilán, Francisco J; Gomes, Nuno; Sánchez-Pérez, Ana María; García-Arnáez, Iñaki; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Ediciones Peldaño (2017-12)
      Titanium is a biomaterial largely used on dental implant manufacturing. However, as a consequence of its intrinsically low bioactivity, the development of distinct superficial treatments in order to enhance its ...

    • openAccess   Protein adsorption/desorption dynamics on Ca‑enriched titanium surfaces: biological implications 

      Romero-Gavilán, Francisco J; Cerqueira, Andreia; Anitua, Eduardo; Tejero, Ricardo; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Izquierdo Escrig, Raul; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Springer (2021-08-27)
      Calcium ions are used in the development of biomaterials for the promotion of coagulation, bone regeneration, and implant osseointegration. Upon implantation, the time-dependent release of calcium ions from titanium implant ...

    • openAccess   Proteome analysis of human serum proteins adsorbed onto different titanium surfaces used in dental implants 

      Romero-Gavilán, Francisco J; Gomes, N. C.; Ródenas, Joaquin; Sánchez, Ana; Azkargorta, Mikel; Iloro, Ibon; Elortza, Felix; García-Arnáez, Iñaki; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Taylor & Francis (2017)
      Titanium dental implants are commonly used due to their biocompatibility and biochemical properties; blasted acid-etched Ti is used more frequently than smooth Ti surfaces. In this study, physico-chemical characterisation ...

    • openAccess   Proteomic analysis of calcium-enriched sol–gel biomaterials 

      Romero-Gavilán, Francisco J; Gomes, Nuno; Cerqueira, Andreia; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Azkargorta, Mikel; Iloro, Ibon; Elortza, Felix; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Springer (2019-04)
      Calcium is an element widely used in the development of biomaterials for bone tissue engineering as it plays important roles in bone metabolism and blood coagulation. The Ca ions can condition the microenvironment at the ...

    • openAccess   Proteomic evaluation of human osteoblast responses to titanium implants over time 

      Romero-Gavilán, Francisco J; Cerqueira, Andreia; García-Arnáez, Iñaki; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Wiley (2022-08-30)
      Titanium is widely used in bone prostheses due to its excellent biocompatibility and osseointegration capacity. To understand the effect of sandblasted acid-etched (SAE) Ti implants on the biological responses of human ...

    • openAccess   Proteomics as a tool to study the osteoimmunomodulatory role of metallic ions in a sol–gel coating 

      García-Arnáez, Iñaki; Romero-Gavilán, Francisco J; Cerqueira, Andreia; Azkargorta, Mikel; Elortza, Félix; Suay, Julio; Goñi, Isabel; Gurruchaga, Mariló Royal Society of Chemistry (2023)
      The success of bone implants depends on the osteoimmunomodulatory (OIM) activity of the biomaterials in the interactions with the periimplantary tissues. Many in vitro tests have been conducted to evaluate the osteoimmunology ...

    • openAccess   The effect of calcium–magnesium mixtures in sol–gel coatings on bone tissue regeneration 

      Cerqueira, Andreia; García-Arnáez, Iñaki; Muriach, Maria; Azkargorta, Mikel; Elortza, Felix; Izquierdo, Raúl; Romero-Gavilán, Francisco J; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Royal Society of Chemistry (2022)
      Calcium and magnesium are two elements essential for bone structure and metabolism. However, their synergistic or competitive effects on bone regeneration are often overlooked during biomaterial development. We examined ...

    • openAccess   The effect of strontium incorporation into sol-gel biomaterials on their protein adsorption and cell interactions 

      Romero-Gavilán, Francisco J; Gomes, Nuno; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Elortza, Felix; Azkargorta, Mikel; Iloro, Ibon; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Elsevier (2019-02-01)
      It is known strontium can both inhibit the osteoclast formation and stimulate the osteoblast maturation, so biomaterials containing this element can favour bone structure stabilisation. The addition of Sr to biomaterials ...