Listar por autoría "a2f03226-a721-4d60-aa98-fdb7e404d912"
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The role of streptavidin and its variants in catalysis by biotinylated secondary amines
Royal Society of Chemistry (2021-11-15)Here, we combine the use of host screening, protein crystallography and QM/MM molecular dynamics simulations to investigate how the protein structure affects iminium catalysis by biotinylated secondary amines in a model ... -
Transfer hydrogenations catalyzed by streptavidin-hosted secondary amine organocatalysts
Royal Society of Chemistry (2021-02-21)Here, the streptavidin–biotin technology was applied to enable organocatalytic transfer hydrogenation. By introducing a biotintethered pyrrolidine (1) to the tetrameric streptavidin (T-Sav), the resulting hybrid catalyst ...
