• openAccess   N-alpha-Aminoacyl Colchicines as Promising Anticancer Agents 

      Marzo Mas, Ana; Conesa Milián, Laura; Noppen, Sam; Liekens, Sandra; Falomir, Eva; Murga, Juan; Carda, Miguel; Marco, J. Alberto Bentham Science Publishers (2020-12-29)
      Background: In the last years, many efforts have been made to find colchicine derivatives with reduced toxicity. Additionally, the deregulation of amino acid uptake by cancer cells provides an opportunity to improve ...
    • openAccess   Synthesis and biological evaluation of carbamates derived from aminocombretastatin A-4 as vascular disrupting agents 

      Conesa Milián, Laura; Falomir, Eva; Murga, Juan; Carda, Miguel; Meyen, Eef; Liekens, Sandra; Marco, J. Alberto Elsevier (2018-03-10)
      A series of t wenty-six carbamates derived from aminocombretastatin A- 4 (AmCA-4 ) were syn thesized and evaluated for their capacity to affect cell proliferation, tubulin polymerization, mitotic cell arrest, microtubule ...