Listar por autoría "911038ff-83a3-4f96-a250-2659abb23e02"
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Advances in the Development of SARS-CoV-2 Mpro Inhibitors
Agost Beltrán, Laura; de la hoz rodriguez, Sergio; Bou Iserte, Lledó; Rodríguez, Santiago; Fernández de la Pradilla Ibáñez, Adrián; González, Florenci MDPI (2022-04-14)Since the outbreak of COVID-19, one of the strategies used to search for new drugs has been to find inhibitors of the main protease (Mpro) of the virus SARS-CoV-2. Initially, previously reported inhibitors of related ... -
Synthesis of a cysteine protease inhibitor with a clickable moiety and its derivation into a potential activity based probe
Fernández de la Pradilla Ibáñez, Adrián Universitat Jaume I (2020-07-10)This work is focused on the design and development of a new chemical probe derived from a new cysteine protease inhibitor. The three main parts of the inhibitor are a warhead with an epoxyketone moiety, a linker with two ...