• openAccess   A High Dietary Glycemic Index Increases Total Mortality in a Mediterranean Population at High Cardiovascular Risk 

      Castro-Quezada, Itandehui; Sánchez-Villegas, Almudena; Estruch, Ramon; Salas-Salvadó, Jordi; Corella, Dolores; Schoreder, Helmut; Álvarez-Pérez, Jacqueline; Ruiz-López, María Dolores; Artacho, Reyes; Ros, Emilio; Bulló, Mònica; Covas Planells, María Isabel; Ruiz-Gutiérrez, Valentina; Ruiz-Canela, Miguel; Buil-Cosiales, Pilar; Gómez-Gracia, Enrique; Lapetra, José; Pintó, Xavier; Arós, Fernando; Fiol Ramis, Miquel; Lamuela Raventós, Rosa María; Martínez González, Miguel Ángel; Serra-Majem, Lluis; PREDIMED Investigators Public Library of Science (2014)
      Objective: Different types of carbohydrates have diverse glycemic response, thus glycemic index (GI) and glycemic load (GL) are used to assess this variation. The impact of dietary GI and GL in all-cause mortality is ...
    • openAccess   Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulate by diet, being higher when adherence to the Mediterranean diet pattern is low 

      Coltell, Oscar; Martínez González, Miguel Ángel; Salas-Salvadó, Jordi; Arós, Fernando; Lapetra, José; Serra-Majem, Lluis; Gómez Gracia, Enrique; Fiol Ramis, Miquel; Sáez Tormo, Guillermo; Pintó, Xavier; Muñoz, Miguel Ángel; Ordovás Muñoz, José M.; Estruch, Ramon; Corella, Dolores; CAROLINA, ORTEGA-AZORÍN; Sorlí, José V; Asensio, Eva Maria; Covas Planells, María Isabel; Ros, Emilio BioMed Central (2012-11)
      Background: Although the Fat Mass and Obesity (FTO) and Melanocortin-4 Receptor (MC4R) genes have been consistently associated with obesity risk, the association between the obesity-risk alleles with type 2 diabetes is ...
    • closedAccess   Effects of total dietary polyphenols on plasma nitric oxide and blood pressure in a high cardiovascular risk cohort. The PREDIMED randomized trial 

      Medina Remón, A.; Tresserra-Rimbau, Anna; Pons, A.; Tur, Josep; Martorell, M.; Ros, E.; Buil-Cosiales, Pilar; Sacanella, E.; Covas Planells, María Isabel; Corella, Dolores; Salas-Salvadó, Jordi; Gómez Gracia, Enrique; Ruiz-Gutiérrez, Valentina; Ortega-Calvo, Manuel; García Valdueza, M.; Arós, Fernando; Saez, G.T.; Serra-Majem, Lluis; Pintó, Xavier; Vinyoles, E.; Estruch, Ramon; Lamuela Raventós, Rosa María Elsevier (2015)
      Background and aim: Hypertension is one of the main cardiovascular risk factors in the elderly. The aims of this work were to evaluate if a one-year intervention with two Mediterranean diets (Med-diet) could decrease ...
    • closedAccess   In vivo transcriptomic profile after a Mediterranean diet in high–cardiovascular risk patients: a randomized controlled trial 

      Castañer, Olga; Corella, Dolores; Covas Planells, María Isabel; Subirana, Isaac; Flores Mateo, Gemma; Nonell, Lara; Bulló, Mònica; De la Torre, Rafael; Portolés, Olga; Fitó, Montserrat American Society for Nutrition (2013)
      Background: Nutrients can exert healthy effects through nutrigenomic modulation. Data are scarce concerning the in vivo effect of a sustained traditional Mediterranean diet (TMD) pattern on the whole transcriptomic ...
    • openAccess   Mediterranean Diet Reduces the Adverse Effect of the TCF7L2-rs7903146 Polymorphism on Cardiovascular Risk Factors and Stroke Incidence 

      Corella, Dolores; Carrasco, Paula; Sorlí, José V; Estruch, Ramon; Rico Sanz, Jesús; Martínez González, Miguel Ángel; Salas-Salvadó, Jordi; Covas Planells, María Isabel; Coltell, Oscar; Arós, Fernando; Lapetra, José; Serra-Majem, Lluis; Ruiz-Gutiérrez, Valentina; Warnberg, Julia; Fiol Ramis, Miquel; Pintó, Xavier; CAROLINA, ORTEGA-AZORÍN; Muñoz, Miguel Ángel; Martínez, J. Alfredo; Gómez Gracia, Enrique; González, José I.; Ros, Emilio; Ordovás Muñoz, José M. American Diabetes Association (2013)
      OBJECTIVE Transcription factor 7-like 2 (TCF7L2) polymorphisms are strongly associated with type 2 diabetes, but controversially with plasma lipids and cardiovascular disease. Interactions of the Mediterranean diet (MedDiet) ...
    • closedAccess   Nutritional adequacy according to carbohydrates and fat quality 

      Sánchez-Tainta, Ana; Zazpe, Itziar; Bes-Rastrollo, Maira; Salas-Salvadó, Jordi; Bulló, Mònica; Sorlí, José V; Corella, Dolores; Covas Planells, María Isabel; Arós, Fernando; Gutiérrez-Bedmar, Mario; Fiol Ramis, Miquel; De la Corte, F. García; Serra-Majem, Lluis; Pintó, Xavier; Schoreder, Helmut; Ros, Emilio; López-Sabater, Maria Carmen; Estruch, Ramon; Martínez González, Miguel Ángel; Coltell, Oscar Springer Verlag (2016)
      Purpose To investigate the association between carbohydrate quality, fat quality or adherence to the Mediterranean diet and intake adequacy of 19 micronutrients in the PREDIMED (PREvención con DIeta MEDiterránea) trial, ...
    • openAccess   Statistical and biological gene-lifestyle interactions of MC4R and FTO with Diet and physical activity on obesity: new effects on alcohol consumption 

      Corella, Dolores; CAROLINA, ORTEGA-AZORÍN; Sorlí, José V; Covas Planells, María Isabel; Carrasco, Paula; Salas-Salvadó, Jordi; Martínez González, Miguel Ángel; Arós, Fernando; Lapetra, José; Serra-Majem, Lluis; Lamuela Raventós, Rosa María; Gómez García, Enrique; Fiol Ramis, Miquel; Pintó, Xavier; Ros, Emilio; Martí, Amelia; Coltell, Oscar; Ordovás Muñoz, José M.; Estruch, Ramon Public Library of Science (2012)
      Background: Fat mass and obesity (FTO) and melanocortin-4 receptor (MC4R) and are relevant genes associated with obesity. This could be through food intake, but results are contradictory. Modulation by diet or other ...