Listar por autoría "573a8599-ee39-4237-8422-fd7565ace11d"
Mostrando ítems 1-12 de 12
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A possible use of melatonin in the dental field: Protein adsorption andinvitrocell response on coated titanium
Cerqueira, Andreia; Romero-Gavilán, Francisco J; Araújo-Gomes, Nuno; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Elsevier (2020)Melatonin (MLT) is widely known for regulating the circadian cycles and has been studied for its role in boneregeneration and inflammation. Its application as a coating for dental implants can condition the local ... -
Axonal extension from dorsal root ganglia on fibrillar and highly aligned poly(lactic acid)-polypyrrole substrates obtained by two different techniques: Electrospun nanofibres and extruded microfibres
Gisbert Roca, Fernando; Más-Estellés, Jorge; MONLEÓN PRADAS, MANUEL; Martinez Ramos, Cristina Elsevier (2020-09-24)The biological behaviour of Schwann cells (SCs) and dorsal root ganglia (DRG) on fibrillar, highly aligned and electroconductive substrates obtained by two different techniques is studied. Mats formed by nanometer-sized ... -
Bioactive zinc-doped sol-gel coating modulates protein adsorption patterns and in vitro cell responses
Cerqueira, Andreia; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Iloro, Ibon; Azkargorta, Mikel; Elortza, Felix; Izquierdo Escrig, Raul; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Elsevier (2020-12-30)Zinc is an essential element with an important role in stimulating the osteogenesis and mineralization and suppressing osteoclast differentiation. In this study, new bioactive ZnCl2-doped sol-gel materials were designed ... -
Characterization of magnesium doped sol-gel biomaterial for bone tissue regeneration: The effect of Mg ion in protein adsorption
Cerqueira, Andreia; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Izquierdo Escrig, Raul; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Elsevier (2021-06-01)Magnesium is the fourth most abundant element in the human body with a wide battery of functions in the maintenance of normal cell homeostasis. In the bone, this element incorporates in the hydroxyapatite structure and it ... -
Complement proteins regulating macrophage polarisation on biomaterials
Gomes, Nuno; Romero-Gavilán, Francisco J; Zhang, Yiyue; Martinez Ramos, Cristina; Elortza, Felix; Azkargorta, Mikel; Martín de Llano, J. J.; GURRUCHAGA, MARILO; Goñi, Isabel; van den Beucken, J.J.J.P.; Suay, Julio Elsevier (2019-09-01)One of the events occurring when a biomaterial is implanted in an host is the protein deposition onto its surface, which might regulate cell responses. When a biomaterial displays a compromised biocompatibility, distinct ... -
Conduits based on the combination of hyaluronic acid and silk fibroin: Characterization, in vitro studies and in vivo biocompatibility
Gisbert, Fernando; Lozano Picazo, Paloma; Pérez-Rigueiro, José; GUINEA TORTUERO, GUSTAVO VICTOR; MONLEÓN PRADAS, MANUEL; Martinez Ramos, Cristina Elsevier (2020-01-16)We address the production of structures intended as conduits made from natural biopolymers, capable of promoting the regeneration of axonal tracts. We combine hyaluronic acid (HA) and silk fibroin (SF) with the aim of ... -
Electrical Stimulation Increases Axonal Growth from Dorsal Root Ganglia Co-Cultured with Schwann Cells in Highly Aligned PLA-PPy-Au Microfiber Substrates
Martinez Ramos, Cristina; Gisbert Roca, Fernando; Serrano Requena, Sara; MONLEÓN PRADAS, MANUEL MDPI (2022-06-07)Nerve regeneration is a slow process that needs to be guided for distances greater than 5 mm. For this reason, different strategies are being studied to guide axonal growth and accelerate the axonal growth rate. In this ... -
Influence of calcium ion-modified implant surfaces in protein adsorption and implant integration
Anitua, Eduardo; Cerqueira, Andreia; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Azkagorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio; Tejero, Ricardo Springer (2021-04-21)Calcium (Ca) is a well-known element in bone metabolism and blood coagulation. Here, we investigate the link between the protein adsorption pattern and the in vivo responses of surfaces modified with calcium ions (Ca-ion) ... -
Osseointegration mechanisms: a proteomic approach
Gomes, Nuno; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Sánchez-Pérez, Ana María; Azkargorta, Mikel; Elortza, Felix; Martín de Llano, J.J.; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Springer-Verlag (2018-03)The prime objectives in the development of biomaterials for dental applications are to improve the quality of osseointegration and to short the time needed to achieve it. Design of implants nowadays involves changes in ... -
Protein adsorption/desorption dynamics on Ca‑enriched titanium surfaces: biological implications
Romero-Gavilán, Francisco J; Cerqueira, Andreia; Anitua, Eduardo; Tejero, Ricardo; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Izquierdo Escrig, Raul; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Springer (2021-08-27)Calcium ions are used in the development of biomaterials for the promotion of coagulation, bone regeneration, and implant osseointegration. Upon implantation, the time-dependent release of calcium ions from titanium implant ... -
Proteomic analysis of calcium-enriched sol–gel biomaterials
Romero-Gavilán, Francisco J; Gomes, Nuno; Cerqueira, Andreia; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Azkargorta, Mikel; Iloro, Ibon; Elortza, Felix; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Springer (2019-04)Calcium is an element widely used in the development of biomaterials for bone tissue engineering as it plays important roles in bone metabolism and blood coagulation. The Ca ions can condition the microenvironment at the ... -
The effect of strontium incorporation into sol-gel biomaterials on their protein adsorption and cell interactions
Romero-Gavilán, Francisco J; Gomes, Nuno; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Elortza, Felix; Azkargorta, Mikel; Iloro, Ibon; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Elsevier (2019-02-01)It is known strontium can both inhibit the osteoclast formation and stimulate the osteoblast maturation, so biomaterials containing this element can favour bone structure stabilisation. The addition of Sr to biomaterials ...