Listar por autoría "28863090-bf09-43f9-91a3-eb0d5037e6b0"
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A possible use of melatonin in the dental field: Protein adsorption andinvitrocell response on coated titanium
Elsevier (2020)Melatonin (MLT) is widely known for regulating the circadian cycles and has been studied for its role in boneregeneration and inflammation. Its application as a coating for dental implants can condition the local ... -
Bioactive potential of silica coatings and its effect on the adhesion of proteins to titanium implants
Elsevier (2018-02-01)There is an ever-increasing need to develop dental implants with ideal characteristics to achieve specific and desired biological response in the scope of improve the healing process post-implantation. Following that ...
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Bioactive zinc-doped sol-gel coating modulates protein adsorption patterns and in vitro cell responses
Elsevier (2020-12-30)Zinc is an essential element with an important role in stimulating the osteogenesis and mineralization and suppressing osteoclast differentiation. In this study, new bioactive ZnCl2-doped sol-gel materials were designed ...
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Characterization of magnesium doped sol-gel biomaterial for bone tissue regeneration: The effect of Mg ion in protein adsorption
Elsevier (2021-06-01)Magnesium is the fourth most abundant element in the human body with a wide battery of functions in the maintenance of normal cell homeostasis. In the bone, this element incorporates in the hydroxyapatite structure and it ...
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Characterization of serum proteins attached to distinct sol–gel hybrid surfaces
Wiley (2017-07)The success of a dental implant depends on its osseointegration, an important feature of the implant biocompatibility. In this study, two distinct sol–gel hybrid coating formulations [50% methyltrimethoxysilane: 50% ...
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Complement proteins regulating macrophage polarisation on biomaterials
Elsevier (2019-09-01)One of the events occurring when a biomaterial is implanted in an host is the protein deposition onto its surface, which might regulate cell responses. When a biomaterial displays a compromised biocompatibility, distinct ...
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Complex effects of Mg-biomaterials on the osteoblast cell machinery: A proteomic study
Elsevier (2022)The cell–biomaterial interface is highly complex; thousands of molecules and many processes participate in its formation. Growing demand for improved biomaterials has highlighted the need to understand the structure and ...
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Correlation between biological responses in vitro and in vivo to Ca-doped sol-gel coatings assessed using proteomic analysis
Elsevier (2022-10-21)Poor correlation between the results of in vitro testing and the subsequent in vivo experiments hinders the design of biomaterials. Thus, new characterisation methods are needed. This study used proteomic and histological ...
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Development and characterisation of strontium-doped sol-gel coatings to optimise the initial bone regeneration processes
Elsevier (2022)Strontium plays an important role in bone regeneration; it promotes the differentiation and maturation of osteoblasts and inhibits the activity of osteoclasts. Our principal objective in this study was to formulate new ...
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Osseointegration mechanisms: a proteomic approach
Springer-Verlag (2018-03)The prime objectives in the development of biomaterials for dental applications are to improve the quality of osseointegration and to short the time needed to achieve it. Design of implants nowadays involves changes in ...
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Osteointegración de implantes de titanio con superficies activas. Un estudio proteómico
Ediciones Peldaño (2017-12)Titanium is a biomaterial largely used on dental implant manufacturing. However, as a consequence of its intrinsically low bioactivity, the development of distinct superficial treatments in order to enhance its ...
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Protein adsorption/desorption dynamics on Ca‑enriched titanium surfaces: biological implications
Springer (2021-08-27)Calcium ions are used in the development of biomaterials for the promotion of coagulation, bone regeneration, and implant osseointegration. Upon implantation, the time-dependent release of calcium ions from titanium implant ...
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Proteome analysis of human serum proteins adsorbed onto different titanium surfaces used in dental implants
Taylor & Francis (2017)Titanium dental implants are commonly used due to their biocompatibility and biochemical properties; blasted acid-etched Ti is used more frequently than smooth Ti surfaces. In this study, physico-chemical characterisation ...
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Proteomic analysis of calcium-enriched sol–gel biomaterials
Springer (2019-04)Calcium is an element widely used in the development of biomaterials for bone tissue engineering as it plays important roles in bone metabolism and blood coagulation. The Ca ions can condition the microenvironment at the ...
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Proteomic Analysis of Mesenchymal Stem Cells and Monocyte Co-Cultures Exposed to a Bioactive Silica-Based Sol–Gel Coating
American Chemical Society (2023)New methodologies capable of extensively analyzing the cell-material interactions are necessary to improve current in vitro characterization methods, and proteomics is a viable alternative. Also, many studies are focused ...
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Proteomic analysis of silica hybrid sol-gel coatings: a potential tool for predicting the biocompatibility of implants in vivo
Taylor & Francis (2017)The interactions of implanted biomaterials with the host organism determine the success or failure of an implantation. Normally, their biocompatibility is assessed using in vitro tests. Unfortunately, in vitro and in vivo ...
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Proteomic evaluation of human osteoblast responses to titanium implants over time
Wiley (2022-08-30)Titanium is widely used in bone prostheses due to its excellent biocompatibility and osseointegration capacity. To understand the effect of sandblasted acid-etched (SAE) Ti implants on the biological responses of human ...
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Proteomics as a tool to study the osteoimmunomodulatory role of metallic ions in a sol–gel coating
Royal Society of Chemistry (2023)The success of bone implants depends on the osteoimmunomodulatory (OIM) activity of the biomaterials in the interactions with the periimplantary tissues. Many in vitro tests have been conducted to evaluate the osteoimmunology ...
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Silica-gelatin hybrid sol-gel coatings: A proteomic study with biocompatibility implications
Wiley (2018-05)Osseointegration, including the foreign body reaction to biomaterials, is an immune‐modulated, multifactorial, and complex healing process in which various cells and mediators are involved. The buildup of the osseointegration ...
