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dc.contributor.authorCherta Cucala, Laura
dc.contributor.authorPortolés Nicolau, Tania
dc.contributor.authorBeltrán Arandes, Joaquim
dc.contributor.authorPitarch Arquimbau, María Elena
dc.contributor.authorMol, Johannes G. J.
dc.contributor.authorHernández Hernández, Félix
dc.date.accessioned2014-05-21T08:56:09Z
dc.date.available2014-05-21T08:56:09Z
dc.date.issued2013-11
dc.identifier.urihttp://hdl.handle.net/10234/92971
dc.description.abstractA multi-residue method for the determination of 142 pesticide residues in fruits and vegetables has been developed using a new atmospheric pressure chemical ionization (APCI) source for coupling gas chromatography (GC) to tandem mass spectrometry (MS). Selected reaction monitoring (SRM) mode has been applied, acquiring three transitions for each compound. In contrast to the extensive fragmentation typically obtained in classical electron ionization (EI), the soft APCI ionization allowed the selection of highly abundant protonated molecules ([M+H]+) as precursor ions for most compounds. This was favorable for both sensitivity and selectivity. Validation of the method was performed in which both quantitative and qualitative parameters were assessed using orange, tomato and carrot samples spiked at two levels, 0.01 and 0.1 mg/kg. The QuEChERS method was used for sample preparation, followed by a 10-fold dilution of the final acetonitrile extract with a mixture of hexane and acetone. Recovery and precision were satisfactory in the three matrices, at both concentration levels. Very low limits of detection (down 0.01 μg/kg for the most sensitive compounds) were achieved. Ion ratios were consistent and identification according to EU criteria was possible in 80% (0.01 mg/kg) to 96% (0.1 mg/kg) of the pesticide/matrix combinations. The method was applied to the analysis of various fruits and vegetables from the Mediterranean region of Spain.ca_CA
dc.format.extent16 p.ca_CA
dc.format.mimetypeapplication/pdfca_CA
dc.language.isoengca_CA
dc.publisherElsevierca_CA
dc.relation.isPartOfJournal of Chromatography A Volume 1314, November 2013ca_CA
dc.rights(c) Elsevierca_CA
dc.subjectAtmospheric pressure chemical ionizationca_CA
dc.subjectGas chromatographyca_CA
dc.subjectTandem mass spectrometryca_CA
dc.subjecttriple quadrupole mass spectrometryca_CA
dc.subjectPesticidesca_CA
dc.subjectFruit and vegetable analysisca_CA
dc.subjectvalidationca_CA
dc.subjectIdentificationca_CA
dc.titleApplication of gas chromatography–(triple quadrupole) mass spectrometry with atmospheric pressure chemical ionization for the determination of multiclass pesticides in fruits and vegetablesca_CA
dc.typeinfo:eu-repo/semantics/articleca_CA
dc.identifier.doihttp://dx.doi.org/10.1016/j.chroma.2013.09.029
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessca_CA
dc.relation.publisherVersionhttp://www.sciencedirect.com/science/article/pii/S002196731301457Xca_CA


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