Gender differences in the neurotoxicity of metals in children
Impacto
Scholar |
Otros documentos de la autoría: Llop, Sabrina; López Espinosa, María José; Rebagliato, Marisa; Ballester, Ferran
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Mostrar el registro completo del ítemcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/36080
comunitat-uji-handle3:10234/36082
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http://dx.doi.org/10.1016/j.tox.2013.04.015 |
Metadatos
Título
Gender differences in the neurotoxicity of metals in childrenFecha de publicación
2013-09Editor
ElsevierCita bibliográfica
LLOP, Sabrina, et al. Gender differences in the neurotoxicity of metals in children. Toxicology, 2013, vol. 311, no 1, p. 3-12.Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
http://www.sciencedirect.com/science/article/pii/S0300483X13001194Versión
info:eu-repo/semantics/publishedVersionPalabras clave / Materias
Resumen
Gender-related differences in susceptibility to chemical exposure to neurotoxicants have not received sufficient attention. Although a significant number of epidemiological studies on the neurodevelopmental effects ... [+]
Gender-related differences in susceptibility to chemical exposure to neurotoxicants have not received sufficient attention. Although a significant number of epidemiological studies on the neurodevelopmental effects of metal exposure has been published in the last twenty years, not many of them have considered the possible gender-specific effects of such exposure. This review is focused on studies where the gender differences in pre- and/or postnatal exposure/s to five metals (mercury, lead, manganese, cadmium, and arsenic) and neurodevelopment were evaluated.
We conducted a PubMed search in December 2012 and retrieved 20 studies that met the inclusion criteria. A large body of literature on potential neurodevelopment effects in children due to mercury exposure is available, but, a clear pattern regarding gender differences in neurotoxicity is not elucidated. There is also abundant available information on the gender-specific health effects of lead, and exposure to this metal seems to affect boys more than girls. Information regarding gender differences in susceptibility of manganese, cadmium, and arsenic is still too scarce to draw any definite conclusion.
More research is highly warranted about this matter. Environmental epidemiological studies should be designed to quantify differential gender-based exposures and outcomes, and this may provide new insights into prevention strategies. [-]
Publicado en
Toxicology Volume 311, Issues 1–2, 6 September 2013Derechos de acceso
http://rightsstatements.org/vocab/CNE/1.0/
info:eu-repo/semantics/restrictedAccess
info:eu-repo/semantics/restrictedAccess
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