Listar LSI_Articles por autoría "e2c2583a-c545-480a-a976-da02091ae56b"
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A High Dietary Glycemic Index Increases Total Mortality in a Mediterranean Population at High Cardiovascular Risk
Castro-Quezada, Itandehui; Sánchez-Villegas, Almudena; Estruch, Ramon; Salas-Salvadó, Jordi; Corella, Dolores; Schoreder, Helmut; Álvarez-Pérez, Jacqueline; Ruiz-López, María Dolores; Artacho, Reyes; Ros, Emilio; Bulló, Mònica; Covas Planells, María Isabel; Ruiz-Gutiérrez, Valentina; Ruiz-Canela, Miguel; Buil-Cosiales, Pilar; Gómez-Gracia, Enrique; Lapetra, José; Pintó, Xavier; Arós, Fernando; Fiol Ramis, Miquel; Lamuela Raventós, Rosa María; Martínez González, Miguel Ángel; Serra-Majem, Lluis; PREDIMED Investigators Public Library of Science (2014)Objective: Different types of carbohydrates have diverse glycemic response, thus glycemic index (GI) and glycemic load (GL) are used to assess this variation. The impact of dietary GI and GL in all-cause mortality is ... -
Amino acid change in the carbohydrate response element binding protein is associated with lower triglycerides and myocardial infarction incidence depending on level of adherence to the Mediterranean diet in the PREDIMED trial
CAROLINA, ORTEGA-AZORÍN; Sorlí, José V; Estruch, Ramon; Asensio, Eva Maria; Coltell, Oscar; González, José I.; Martínez González, Miguel Ángel; Ros, Emilio; Salas-Salvadó, Jordi; Fitó, Montserrat; Arós, Fernando; Lapetra, José; Serra-Majem, Lluis; Ruiz-Gutiérrez, Valentina; Gómez Gracia, Enrique; Fiol Ramis, Miquel; Flores, Gemma; Pintó, Xavier; Sáiz, Carmen; Ordovás Muñoz, José M.; Corella, Dolores American Heart Association (2014-02)Background: A variant (rs3812316, C771G, Gln241His) in the MLXIPL (Max-like protein X interacting protein-like) gene encoding the carbohydrate response element binding protein has been associated with lower triglycerides. ... -
Association between dietary fibre intake and fruit, vegetable or whole-grain consumption and the risk of CVD: results from the PREvención con DIeta MEDiterránea (PREDIMED) trial
Buil-Cosiales, Pilar; Toledo, Estefanía; Salas-Salvadó, Jordi; Zazpe, Itziar; Farràs, Marta; Basterra-Gortari, Francisco Javier; Díez Espino, Javier; Estruch, Ramon; Corella, Dolores; Ros, Emilio; Marti, Amelia; Gómez Gracia, Enrique; Ortega-Calvo, Manuel; Arós, Fernando; Moñino, Manuel; Serra-Majem, Lluis; Pintó, Xavier; Lamuela Raventós, Rosa María; Babio, Nancy; González, José I.; Fitó, Montserrat; Martínez González, Miguel Ángel Nutrition Society (2016)Prospective studies assessing the association between fibre intake or fibre-rich food consumption and the risk of CVD have often been limited by baseline assessment of diet. Thus far, no study has used yearly repeated ... -
Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulate by diet, being higher when adherence to the Mediterranean diet pattern is low
Coltell, Oscar; Martínez González, Miguel Ángel; Salas-Salvadó, Jordi; Arós, Fernando; Lapetra, José; Serra-Majem, Lluis; Gómez Gracia, Enrique; Fiol Ramis, Miquel; Sáez Tormo, Guillermo; Pintó, Xavier; Muñoz, Miguel Ángel; Ordovás Muñoz, José M.; Estruch, Ramon; Corella, Dolores; CAROLINA, ORTEGA-AZORÍN; Sorlí, José V; Asensio, Eva Maria; Covas Planells, María Isabel; Ros, Emilio BioMed Central (2012-11)Background: Although the Fat Mass and Obesity (FTO) and Melanocortin-4 Receptor (MC4R) genes have been consistently associated with obesity risk, the association between the obesity-risk alleles with type 2 diabetes is ... -
Associations of the MCM6-rs3754686 proxy for milk intake in Mediterranean and American populations with cardiovascular biomarkers, disease and mortality: Mendelian randomization
Smith, C.E.; Coltell, Oscar; Sorlí, José V; Estruch, Ramon; Martínez González, Miguel Ángel; Salas-Salvadó, Jordi; Fitó, Montserrat; Arós, Fernando; Dashti, Hassan S.; Lai, Chao-Qiang; Miró, Leticia; Serra-Majem, Lluis; Gómez Gracia, Enrique; Fiol Ramis, Miquel; Ros, Emilio; Aslibekyan, Stella; Hidalgo, Bertha; Neuhouser, Marian L.; Di, Chongzhi; Tucker, Katherine; Arnett, Donna K.; Ordovás Muñoz, José M.; Corella, Dolores Nature Publishing Group (2016)Controversy persists on the association between dairy products, especially milk, and cardiovascular diseases (CVD). Genetic proxies may improve dairy intake estimations, and clarify diet-disease relationships through ... -
CLOCK gene variation is associated with incidence of type-2 diabetes and cardiovascular diseases in type-2 diabetic subjects: dietary modulation in the PREDIMED randomized trial
Corella, Dolores; Asensio, Eva Maria; Coltell, Oscar; Sorlí, José V; Estruch, Ramon; Martínez González, Miguel Ángel; Castañer, Olga; Arós, Fernando; Lapetra, José; Serra-Majem, Lluis; Gómez Gracia, Enrique; CAROLINA, ORTEGA-AZORÍN; Fiol Ramis, Miquel; Díez Espino, Javier; Díaz López, Andrés; Fitó, Montserrat; Ros, Emilio; Ordovás Muñoz, José M. BioMed Central (2016-01)Background Circadian rhythms regulate key biological processes influencing metabolic pathways. Disregulation is associated with type 2 diabetes (T2D) and cardiovascular diseases (CVD). Circadian rhythms are generated by ... -
Dietary alpha-Linolenic Acid, Marine omega-3 Fatty Acids, and Mortality in a Population With High Fish Consumption: Findings From the PREvención con DIeta MEDiterránea (PREDIMED) Study
Sala-Vila, Aleix; Guash-Ferré, Marta; Hu, Frank B.; Sánchez-Tainta, Ana; Bulló, Mònica; Serra-Mir, Mercè; López-Sabater, Maria Carmen; Sorlí, José V; Arós, Fernando; Fiol Ramis, Miquel; Muñoz, Miguel Ángel; Serra-Majem, Lluis; Martínez, J. Alfredo; Corella, Dolores; Fitó, Montserrat; Salas-Salvadó, Jordi; Martínez González, Miguel Ángel; Estruch, Ramon; Ros, Emilio; Coltell, Oscar; PREDIMED Investigators American Heart Association (2016-01)Background Epidemiological evidence suggests a cardioprotective role of α‐linolenic acid (ALA), a plant‐derived ω‐3 fatty acid. It is unclear whether ALA is beneficial in a background of high marine ω‐3 fatty acids (long‐chain ... -
Effects of the Ser326Cys Polymorphism in the DNA Repair OGG1 Gene on Cancer, Cardiovascular, and All-Cause Mortality in the PREDIMED Study: Modulation by Diet
Corella, Dolores; Ramírez-Sabio, Judith B.; Coltell, Oscar; CAROLINA, ORTEGA-AZORÍN; Estruch, Ramon; Martínez González, Miguel Ángel; Salas-Salvadó, Jordi; Sorlí, José V; Castañer, Olga; Arós, Fernando; García-Corte, Franscisco J.; Serra-Majem, Lluis; Gómez-Gracia, Enrique; Fiol Ramis, Miquel; Pintó, Xavier; Sáez, Guillermo T.; Toledo, Estefanía; Basora, Josep; Fitó, Montserrat; Cofán, Montserrat; Ros, Emilio; Ordovás Muñoz, José M. Elsevier (2018-04)Background Oxidatively induced DNA damage, an important factor in cancer etiology, is repaired by oxyguanine glycosylase 1 (OGG1). The lower repair capacity genotype (homozygote Cys326Cys) in the OGG1-rs1052133 (Ser326Cys) ... -
Frequent Consumption of Sugar- and Artificially Sweetened Beverages and Natural and Bottled Fruit Juices Is Associated with an Increased Risk of Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Disease Risk
Ferreira-Pêgo, Cíntia; Babio, Nancy; Bes-Rastrollo, Maira; Corella, Dolores; Estruch, Ramon; Ros, Emilio; Fitó, Montserrat; Serra-Majem, Lluis; Arós, Fernando; Fiol Ramis, Miquel; Santos Lozano, José Manuel; Muñoz-Bravo, Carlos; Pintó, Xavier; Ruiz-Canela, Miguel; Salas-Salvadó, Jordi; Coltell, Oscar American Society for Nutrition (2016-08)Background: The relation between the consumption of sweetened beverages and metabolic syndrome (MetS) is controversial. Objective: This analysis evaluated the associations between intakes of sugar-sweetened beverages ... -
Intake of Total Polyphenols and Some Classes of Polyphenols Is Inversely Associated with Diabetes in Elderly People at High Cardiovascular Disease Risk
Tresserra-Rimbau, Anna; Guash-Ferré, Marta; Salas-Salvadó, Jordi; Toledo, Estefanía; Corella, Dolores; Castañer, Olga; Guo, Xiaohui; Gómez Gracia, Enrique; Lapetra, José; Arós, Fernando; Fiol Ramis, Miquel; Ros, Emilio; Serra-Majem, Lluis; Pintó, Xavier; Fitó, Montserrat; Babio, Nancy; Martínez González, Miguel Ángel; Sorlí, José V; López-Sabater, Maria Carmen; Estruch, Ramon; Lamuela Raventós, Rosa María; Coltell, Oscar; PREDIMED Investigators American Society for Nutrition (2016-03)Background: Higher consumption of some polyphenols has been associated with a reduced risk of diabetes. However, no studies have evaluated the relation between all polyphenol subclasses and the incidence of diabetes. Objective: ... -
Inverse association between habitual polyphenol intake and incidence of cardiovascular events in the PREDIMED study
Tresserra-Rimbau, Anna; Rimm, Eric B.; Medina Remón, A.; Martínez González, Miguel Ángel; De la Torre, R.; Corella, Dolores; Salas-Salvadó, Jordi; Gómez Gracia, Enrique; Lapetra, José; Arós, Fernando; Fiol Ramis, Miquel; Ros, Emilio; Serra-Majem, Lluis; Pintó, Xavier; Sáez Tormo, Guillermo; Basora, Josep; Sorlí, José V; Martínez, J. Alfredo; Vinyoles, E.; Ruiz-Gutiérrez, Valentina; Estruch, Ramon; Lamuela Raventós, Rosa María; Coltell, Oscar Elsevier (2016-06)Background and aims Epidemiologic and biological evidence supports an inverse association between polyphenol consumption and the risk of cardiovascular disease (CVD). However, no previous studies have prospectively ... -
Mediterranean Diet Reduces the Adverse Effect of the TCF7L2-rs7903146 Polymorphism on Cardiovascular Risk Factors and Stroke Incidence
Corella, Dolores; Carrasco, Paula; Sorlí, José V; Estruch, Ramon; Rico Sanz, Jesús; Martínez González, Miguel Ángel; Salas-Salvadó, Jordi; Covas Planells, María Isabel; Coltell, Oscar; Arós, Fernando; Lapetra, José; Serra-Majem, Lluis; Ruiz-Gutiérrez, Valentina; Warnberg, Julia; Fiol Ramis, Miquel; Pintó, Xavier; CAROLINA, ORTEGA-AZORÍN; Muñoz, Miguel Ángel; Martínez, J. Alfredo; Gómez Gracia, Enrique; González, José I.; Ros, Emilio; Ordovás Muñoz, José M. American Diabetes Association (2013)OBJECTIVE Transcription factor 7-like 2 (TCF7L2) polymorphisms are strongly associated with type 2 diabetes, but controversially with plasma lipids and cardiovascular disease. Interactions of the Mediterranean diet (MedDiet) ... -
MicroRNA-410 regulated lipoprotein lipase variant rs13702 is associated with stroke incidence and modulated by diet in the randomized controlled PREDIMED trial
Corella, Dolores; Sorlí, José V; Estruch, Ramon; Coltell, Oscar; CAROLINA, ORTEGA-AZORÍN; Portolés, Olga; Martínez González, Miguel Ángel; Bulló, Mònica; Fitó, Montserrat; Arós, Fernando; Lapetra, José; Asensio, Eva Maria; Sáez Tormo, Guillermo; Serra-Majem, Lluis; Muñoz Bravo, Carlos; Ruiz-Gutiérrez, Valentina; Fiol Ramis, Miquel; Vinyoles, Ernest; Pintó, Xavier; Richardson, Kris; Ros, Emilio; Ordovás Muñoz, José M. American Society for Nutrition (2014-08)Background: MicroRNAs have emerged as important epigenetic regulators in cardiovascular diseases (CVDs). Using an observational meta-analysis design, we previously characterized a gain-of-function microRNA-410 target site ... -
Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial
Corella, Dolores; Sorlí, José V; González, José I.; CAROLINA, ORTEGA-AZORÍN; Fitó, Montserrat; Bulló, Mònica; Martínez González, Miguel Ángel; Ros, Emilio; Arós, Fernando; Lapetra, José; Gómez Gracia, Enrique; Serra-Majem, Lluis; Ruiz-Gutiérrez, Valentina; Fiol Ramis, Miquel; Coltell, Oscar; Vinyoles, Ernest; Pintó, Xavier; Martí, Amelia; Sáiz, Carmen; Ordovás Muñoz, José M.; Estruch, Ramon BioMed Central (2014-01)Background: The Fas apoptotic pathway has been implicated in type 2 diabetes and cardiovascular disease. Although a polymorphism (rs7138803; G > A) near the Fas apoptotic inhibitory molecule 2 (FAIM2) locus has been related ... -
Nutritional adequacy according to carbohydrates and fat quality
Sánchez-Tainta, Ana; Zazpe, Itziar; Bes-Rastrollo, Maira; Salas-Salvadó, Jordi; Bulló, Mònica; Sorlí, José V; Corella, Dolores; Covas Planells, María Isabel; Arós, Fernando; Gutiérrez-Bedmar, Mario; Fiol Ramis, Miquel; De la Corte, F. García; Serra-Majem, Lluis; Pintó, Xavier; Schoreder, Helmut; Ros, Emilio; López-Sabater, Maria Carmen; Estruch, Ramon; Martínez González, Miguel Ángel; Coltell, Oscar Springer Verlag (2016)Purpose To investigate the association between carbohydrate quality, fat quality or adherence to the Mediterranean diet and intake adequacy of 19 micronutrients in the PREDIMED (PREvención con DIeta MEDiterránea) trial, ... -
Polymorphism of the Transcription Factor 7-Like 2 Gene (TCF7L2) Interacts with Obesity on Type-2 Diabetes in the PREDIMED Study Emphasizing the Heterogeneity of Genetic Variants in Type-2 Diabetes Risk Prediction: Time for Obesity-Specific Genetic Risk Scores
Corella, Dolores; Coltell, Oscar; Sorlí, José V; Estruch, Ramon; Quiles Guiñau, Laura; Martínez González, Miguel Ángel; Salas-Salvadó, Jordi; Castañer, Olga; Arós, Fernando; Ortega-Calvo, Manuel; Serra-Majem, Lluis; Gómez Gracia, Enrique; Portolés, Olga; Fiol Ramis, Miquel; Díez Espino, Javier; Basora, Josep; Fitó, Montserrat; Ros, Emilio; Ordovás Muñoz, José M. MDPI (2016)Nutrigenetic studies analyzing gene–diet interactions of the TCF7L2-rs7903146 C > T polymorphism on type-2 diabetes (T2D) have shown controversial results. A reason contributing to this may be the additional modulation by ... -
PREDIMED Investigators
Díez Espino, Javier; Basterra-Gortari, Francisco Javier; Salas-Salvadó, Jordi; Buil-Cosiales, Pilar; Corella, Dolores; Schröder, Helmut; Estruch, Ramon; Ros, Emilio; Gómez-Gracia, Enrique; Arós, Fernando; Fiol Ramis, Miquel; Lapetra, José; Serra-Majem, Lluis; Pintó, Xavier; Babio, Nancy; Quiles Guiñau, Laura; Fitó, Montserrat; Marti, Amelia; Toledo, Estefanía; PREDIMED Investigators Elsevier (2017)Background Eggs are a major source of dietary cholesterol and their consumption has been sometimes discouraged. A relationship between egg consumption and the incidence of cardiovascular disease (CVD) has been suggested ... -
Statistical and biological gene-lifestyle interactions of MC4R and FTO with Diet and physical activity on obesity: new effects on alcohol consumption
Corella, Dolores; CAROLINA, ORTEGA-AZORÍN; Sorlí, José V; Covas Planells, María Isabel; Carrasco, Paula; Salas-Salvadó, Jordi; Martínez González, Miguel Ángel; Arós, Fernando; Lapetra, José; Serra-Majem, Lluis; Lamuela Raventós, Rosa María; Gómez García, Enrique; Fiol Ramis, Miquel; Pintó, Xavier; Ros, Emilio; Martí, Amelia; Coltell, Oscar; Ordovás Muñoz, José M.; Estruch, Ramon Public Library of Science (2012)Background: Fat mass and obesity (FTO) and melanocortin-4 receptor (MC4R) and are relevant genes associated with obesity. This could be through food intake, but results are contradictory. Modulation by diet or other ...