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Catalytic enantioselective epoxidation of nitroalkenes
(Royal Society of Chemistry, 2016)
Nitroepoxides are potentially exploitable as synthons with vicinal electrophilic centers. Nevertheless, although advances have been made in the field, enantioselective epoxidation of nitroalkenes is still a challenging ...
Novel fluorescent anthracene–bodipy dyads displaying sensitivity to pH and turn-on behaviour towards Cu(II) ions
(Royal Society of Chemistry, 2017)
Three bichromophoric compounds containing anthracene and bodipy moieties connected by different spacers have been synthesized and fully characterized. The set of spacers comprises a variety of bridges (short and flexible ...
Dipeptidyl Nitroalkenes as Potent Reversible Inhibitors of Cysteine Proteases Rhodesain and Cruzain
(American Chemical Society, 2016)
Dipeptidyl nitroalkenes are potent reversible inhibitors of cysteine proteases. Inhibitor 11 resulted to be the most potent one with Ki values of 0.49 and 0.44 nM against rhodesain and cruzain, respectively. According to ...
Synthesis of combretastatin A-4 O-alkyl derivatives and evaluation of their cytotoxic, antiangiogenic and antitelomerase activity
We here report the synthesis and biological evaluation of several combretastatin A-4 derivatives alkylated at the phenol hydroxyl group. Some of these derivatives contain an (E)-arylalkene fragment reminiscent of that ...
Use of granite sludge wastes for the production of coloured cement-based mortars
The value of granite sludge wastes (GS) in cement-based mortar formulations was examined by assessing their potential as structural components and pigments. Full characterization of GS was accomplished by X-ray fluorescence ...
Ratiometric fluorescence sensing of phenylalanine derivatives by synthetic macrocyclic receptors
The supramolecular analytical behavior of eight pseudopeptidic fluorescent receptors (1a-c, 2a-c, 3, 4) has been studied. The receptors are either macrocyclic or open chain derivatives based on the naphthalene chromophore. ...
New polymer-supported photocatalyst with improved compatibility with polar solvents. Synthetic application using solar light as energy source
A new kind of supported photocatalysts derived from low-crosslinked polystrene, containing Rose Bengal and pyridinium groups, is described. Such polymers are capable to catalyze the quantitative synthesis of 5-hydroxy-5H ...
Supramolecular hydrogels for enzymatically triggered self-immolative drug delivery
For the first time the combination of self-immolative spacers and supramolecular hydrogels has been tested in enzyme triggered drug release. Low-molecular weight drug-gelator conjugates have been prepared, which contain a ...
Pd catalysts immobilized onto gel-supported ionic liquid-like phases (g-SILLPs): A remarkable effect of the nature of the support
New polymeric materials containing functional sites analogous to ionic liquids have been synthesized. Those materials are a supported reservoir for the active Pd species. Their catalytic activity has been evaluated for the ...
Synthetic application of photoactive porous monolithic polymers
The oxidation of 2-furoic acid to 5-hydroxy-5H-furan-2-one has been accomplished in quantitative yield in chloroform using a novel supported photocatalyst. This material comprises Rose Bengal grafted to the surface of a ...