Mostrar el registro sencillo del ítem

dc.contributor.authorBijlsma, Lubertus
dc.contributor.authorEmke, Erik
dc.contributor.authorHernandez, Felix
dc.contributor.authorde Voogt, Pim
dc.date.accessioned2013-05-29T11:07:55Z
dc.date.available2013-05-29T11:07:55Z
dc.date.issued2012-11
dc.identifier.issn0045-6535
dc.identifier.urihttp://hdl.handle.net/10234/65093
dc.description.abstractAn extensive study on the presence of illicit drugs and pharmaceuticals with potential for abuse in sewage waters was made for the first time in the Netherlands. A total number of 24 target drugs were investigated in influent and effluent wastewater using liquid chromatography coupled to a high resolution Orbitrap mass spectrometer. This powerful analyzer has allowed not only the detection and identification of the compounds under investigation, but also their quantification at very low levels, which is highly innovative in the field of drugs of abuse. Samples were taken from five sewage treatment plants (STPs) during a whole week. The selected STPs served four cities of different size and an international airport. Daily variances of drug loads were demonstrated and removal efficiencies calculated for each drug and STP individually. Twelve target compounds were found in at least one influent or effluent, and highest concentrations were observed in influents collected from more urbanized areas. The compounds more frequently detected were amphetamine, benzoylecgonine, cocaine and THCsingle bondCOOH together with the pharmaceuticals codeine, oxazepam and temazepam. Established week trends in consumption of drugs showed distinct differences between individual drugs. A slightly different occurrence pattern was observed in wastewaters from the airport. Thus, methamphetamine was only detected at Schiphol, a fact that was interpreted to be caused by consumption of this drug by travelers. Despite the fact that the Netherlands has frequently been criticized for its liberal drug policy the results from this study did not reveal higher drug consumption than found elsewhere, with the exception of cannabis.ca_CA
dc.format.extent8 p.ca_CA
dc.format.mimetypeapplication/pdfca_CA
dc.language.isoengca_CA
dc.publisherElsevierca_CA
dc.relation.isPartOfChemosphere, Vol. 89, num. 11, 2012ca_CA
dc.rightsCopyright © 2012, Elsevierca_CA
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/*
dc.subjectIllicit drugs of abuseca_CA
dc.subjectAccurate massca_CA
dc.subjectLinear ion trap (LTQ FT)ca_CA
dc.subjectOrbitrap mass spectrometryca_CA
dc.subjectSewage waterca_CA
dc.subjectSTP removal efficiencyca_CA
dc.titleInvestigation of drugs of abuse and relevant metabolites in Dutch sewage water by liquid chromatography coupled to high resolution mass spectrometryca_CA
dc.typeinfo:eu-repo/semantics/articleca_CA
dc.identifier.doihttp://dx.doi.org/10.1016/j.chemosphere.2012.05.110
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessca_CA
dc.relation.publisherVersionhttp://www.sciencedirect.com/science/article/pii/S0045653512007576ca_CA
dc.type.versioninfo:eu-repo/semantics/submittedVersion


Ficheros en el ítem

Thumbnail

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem