Mostrar el registro sencillo del ítem
New chiral tetraaza ligands for the efficient enantioselective addition of dialkylzinc to aromatic aldehydes
dc.contributor.author | Burguete, M. Isabel | |
dc.contributor.author | Escorihuela, Jorge | |
dc.contributor.author | Luis, Santiago V. | |
dc.contributor.author | Lledós, Agustí | |
dc.contributor.author | Ujaque, Gregori | |
dc.date.accessioned | 2012-05-28T14:36:49Z | |
dc.date.available | 2012-05-28T14:36:49Z | |
dc.date.issued | 2008 | |
dc.identifier | http://dx.doi.org/10.1016/j.tet.2008.07.099 | |
dc.identifier.citation | Tetrahedron, 64, 41, p. 9717-9724 | |
dc.identifier.issn | 404020 | |
dc.identifier.uri | http://hdl.handle.net/10234/39026 | |
dc.description.abstract | A series of chiral tetraaza ligands were studied for the enantioselective addition of dialkylzinc to aldehydes. These bis(amino amide) ligands show high enantioselectivity in the addition of organozincs to aromatic aldehydes. Different structural elements on the ligands seem to play an important role in determining the observed enantioselectivity. Ligand 4b (N,N′-bis(N-l-valinyl)-1,3-diaminopropane, with an aliphatic spacer with 3C atoms) catalyzed the addition of Et<sub>2</sub>Zn to benzaldehyde, 1-naphtaldehyde, 4-methoxybenzaldehyde, and 4-chlorobenzaldehyde to give the corresponding alcohol products with excellent conversions and selectivities and with enantioselectivities of 99, 97, 98, and 82%, respectively. DFT calculations provide an understanding of the mechanism of the enantioselection process. © 2008 Elsevier Ltd. All rights reserved. | |
dc.language.iso | eng | |
dc.publisher | Elsevier | |
dc.rights.uri | http://rightsstatements.org/vocab/CNE/1.0/ | * |
dc.title | New chiral tetraaza ligands for the efficient enantioselective addition of dialkylzinc to aromatic aldehydes | |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | http://dx.doi.org/10.1016/j.tet.2008.07.099 | |
dc.rights.accessRights | info:eu-repo/semantics/closedAccess |
Ficheros en el ítem
Ficheros | Tamaño | Formato | Ver |
---|---|---|---|
No hay ficheros asociados a este ítem. |
Este ítem aparece en la(s) siguiente(s) colección(ones)
-
QUIO_Articles [690]
Articles de publicacions periòdiques