Listar MED_Articles por título

Mostrando ítems 379-398 de 637

    • openAccess   Naltrexone Reverses Ethanol-Induced Rat Hippocampal and Serum Oxidative Damage 

      Almansa, Inmaculada; Barcia, Jorge M; López-Pedrajas, Rosa; Muriach, Maria; Miranda, María; Romero, Francisco J. Hindawi Publishing Corporation (2013)
      Naltrexone, an antagonist of 𝜇�-opioid receptors, is clinically used as adjuvant therapy of alcohol dishabituation. The aim of the present work was to test the effect of 1 mg/kg body weight of naltrexone to revert oxidative ...

    • openAccess   Neoadjuvant Chemotherapy plus Interval Cytoreductive Surgery with or without Hyperthermic Intraperitoneal Chemotherapy (NIHIPEC) in the Treatment of Advanced Ovarian Cancer: A Multicentric Propensity Score Study 

      Llueca, Antoni; Ibáñez Gual, Maria Victoria; CASCALES SANCHEZ, PEDRO; Gil-Moreno, Antonio; Bebia, Vicente; Ponce, Jordi; Fernandez, Sergi; Arjona-Sanchez, Alvaro; Muruzabal Torquemada, Juan Carlos; Veiga-Canuto, Nadia; Díaz-Feijoo, Berta; Celada Castro, Cristina; Gilabert-Estellés, Juan; AGHABABYAN, KRISTINA; Lacueva, Francisco Javier; Calero, Alicia; Segura-Sampedro, Juan José; Maiocchi, Karina; Llorca Cardeñosa, Sara; Villarín, Álvaro; CLIMENT MARTÍ, MARIA TERESA; Delgado Barriga, Katty; Serra Rubert, Anna; GOMEZ QUILES, LUIS; Llueca, Maria; Spain GOG and GECOP Working Group MDPI (2023-08-26)
      Simple Summary Advanced ovarian cancer (Stages III-IV) continues to be one of the gynecological tumors with the highest mortality. Standard treatment consists of debulking surgery and subsequent adjuvant chemotherapy. ...

    • openAccess   Neural activity patterns in the chemosensory network encoding vomeronasal and olfactory information in mice 

      Pardo-Bellver, Cecília; Vila Martín, Manuel Esteban; Martínez-Bellver, Sergio; Faus, María Villafranca Frontiers Media (2022)
      Rodents detect chemical information mainly through the olfactory and vomeronasal systems, which play complementary roles to orchestrate appropriate behavioral responses. To characterize the integration of chemosensory ...

    • openAccess   Neural Stem Cells as Potential Glioblastoma Cells of Origin 

      Loras Monfort, Alba; Gonzalez Bonet, Luis Germán; Gutierrez-Arroyo, Julia L.; Martinez-Cadenas, Conrado; Marques-Torrejon, Maria Angeles MDPI (2023)
      Glioblastoma multiforme (GBM) is the most malignant brain tumor in adults and it remains incurable. These tumors are very heterogeneous, resistant to cytotoxic therapies, and they show high rates of invasiveness. Therefore, ...

    • openAccess   Neurogenesis of medium spiny neurons in the nucleus accumbens continues into adulthood and is enhanced by pathological pain 

      García-González, Diego; Dumitru, Ionut; Zuccotti, Annalisa; Yen, Ting-Yu; Herranz-Pérez, Vicente; Tan, Linette Liqi; Angela, Neitz; García-Verdugo, Jose Manuel; Kuner, Rohini; Alfonso, Julieta; Monyer, Hannah Springer Nature (2021)
      In mammals, most adult neural stem cells (NSCs) are located in the ventricular–subventricular zone (V-SVZ) along the wall of the lateral ventricles and they are the source of olfactory bulb interneurons. Adult NSCs exhibit ...

    • openAccess   Neuroinflammation as a possible link between attention-deficit/ hyperactivity disorder (ADHD) and pain 

      Kerekes, Nóra; Sánchez-Pérez, Ana María; Landry, Marc ELSEVIER (2021)
      Attention-deficit/hyperactivity disorder (ADHD) and pathological pain are two complex syndromes of multifactorial origin. Despite their prevalence and broad impacts, these conditions are seldom recognized and managed ...

    • openAccess   Neuronal Bioenergetics and Acute Mitochondrial Dysfunction: A Clue to Understanding the Central Nervous System Side Effects of Efavirenz 

      Funes, Haryes A.; Apostolova, Nadezda; Alegre, Fernando; Blas García, Ana; Álvarez, Ángeles; Martí Cabrera, Miguel; Esplugues Mota, Juan V. Oxford University Press (2014-05)
      Background. Neurological pathogenesis is associated with mitochondrial dysfunction and differences in neuronal/glial handling of oxygen and glucose. The main side effects attributed to efavirenz involve the CNS, but the ...

    • openAccess   New GOLD classification: longitudinal data on group assignment 

      Casanova, Ciro; Marin, Jose M.; Martinez-Gonzalez, Cristina; Lucas-Ramos, Pilar de; Mir-Viladrich, Isabel; Cosio, Borja; Peces-Barba, Germán; Calle-Rubio, Miryam; Solanes-García, Ingrid; Agüero Balbin, Ramón; de Diego, Alfredo; Feu-Collado, Nuria; Alfageme Michavila, Inmaculada; Irigaray, Rosa; Balcells, Eva; Llunell Casanovas, Antònia; Bautista i García, Joan Damià; Marín Royo, Margarita; Soler-Cataluña, Juan J.; Lopez-Campos, Jose Luis; Soriano, Joan B.; Torres, Juan P. de; COPD History Assessment In SpaiN (CHAIN) cohort BioMed Central (2014)
      Rationale: Little is known about the longitudinal changes associated with using the 2013 update of the multidimensional GOLD strategy for chronic obstructive pulmonary disease (COPD). Objective: To determine the COPD ...

    • closedAccess   New insights in primary ciliary dyskinesia 

      Reula, Ana; Moreno-Galdó, Antonio; Romero, Teresa; MILARA, JAVIER; Carda, Carmen; Mata Roig, Manuel; Escribano, Amparo; Dasi, Francisco; Armengot Carceller, Amparo; Lucas, J. S. Taylor & Francis (2017)
      Introduction: Primary ciliary dyskinesia (PCD) is a rare genetic disease with an estimated prevalence of 1:20.000 births. It is characterized by abnormal motility of cilia, leading to impaired mucociliary clearance, and ...

    • openAccess   New neurons use Slit-Robo signaling to migrate through the glial meshwork and approach a lesion for functional regeneration 

      Kaneko, Naoko; Herranz-Pérez, Vicente; Otsuka, Takanobu; Sano, H.; Ohno, N.; Omata, T.; Nguyen, Huy Bang; Thai, T.Q.; Nambu, A.; Kawaguchi, Yuki; García-Verdugo, Jose Manuel; Sawamoto, Kazunobu American Association for the Advancement of Science (2018)
      After brain injury, neural stem cell–derived neuronal precursors (neuroblasts) in the ventricular-subventricular zone migrate toward the lesion. However, the ability of the mammalian brain to regenerate neuronal ...

    • openAccess   Nigral degeneration correlates with persistent activation of cerebellar Purkinje cells in MPTP-treated monkeys 

      Heman, Paola; Barcia, Carlos; Gómez, Aurora; Ros Gómez, Carmen María; Ros Bernal, Francisco; Yuste Jiménez, José Enrique; De Pablos, Vicente; Fernández Villalba, Emiliano; Toledo-Cárdenas, María Rebeca; Herrero Ezquerro, María Trinidad Universidad de Murcia (2012)
      In the present work we analyze the cerebellum of chronic parkinsonian monkeys in order to clarify whether chronic mesencephalic depletion is associated with long term activation of the cerebellar neurons in chronic ...

    • openAccess   Non-compliance and therapeutic inertia: two unanswered questions in clinical practice 

      Pallarés-Carratalá, Vicente; Pascual Pérez, R. Informa Healthcare (2014)

    • closedAccess   Non-Invasive Mechanical Ventilation Versus Continuous Positive Airway Pressure Relating to Cardiogenic Pulmonary Edema in an Intensive Care Unit 

      Belenguer-Muncharaz, Alberto; Mateu-Campos, Lidon; González-Luís, Rubén; Vidal-Tegedor, Bárbara; Ferrándiz-Sellés, Amparo; Árguedas-Cervera, Joaquín; Altaba-Tena, Susana; Casero-Roig, Patricia; Moreno-Clarí, Ester Elsevier (2017-10)
      Background To compare the application of non-invasive ventilation (NIV) versus continuous positive airway pressure (CPAP) in the treatment of patients with cardiogenic pulmonary edema (CPE) admitted to an intensive care ...

    • openAccess   Non-neuronal cholinergic system contributes to corticosteroid resistance in chronic obstructive pulmonary disease patients 

      MILARA, JAVIER; Cervera, Angela; de Diego, Alfredo; Sanz, Celia; Juan, Gustavo; Gavaldà, Amadeu; Miralpeix, Montserrat; Morcillo, Esteban; Cortijo, Julio BioMed Central (2016)
      Background: Inhaled corticosteroid (ICS) with long-acting beta-2 agonists is a well-documented combination therapy for chronic obstructive pulmonary disease (COPD) based on its additive anti-inflammatory properties. By ...

    • closedAccess   Noncovalent Peptide Stapling Using Alpha-Methyl-l-Phenylalanine for α-Helical Peptidomimetics 

      Bathgate, Ross A. D.; Praveen, Praveen; Sethi, Ashish; Dhingra, Rishi R.; Kocan, Martina; Ou, Qinghao; Valkovic, Adam L.,; Gil-Miravet, Isis; Navarro Sánchez, Mónica; Olucha-Bordonau, Francisco E; Gundlach, Andrew Lawrence; Rosengren, K. Johan; Dutschmann, Mathias; Hossain, Mohammed Akhter American Chemical Society (2023-08-20)
      Peptides and peptidomimetics are attractive drug candidates because of their high target specificity and low-toxicity profiles. Developing peptidomimetics using hydrocarbon (HC)-stapling or other stapling strategies has ...

    • openAccess   Noninvasive Imaging Estimation of Myocardial Iron Repletion Following Administration of Intravenous Iron: The Myocardial-IRON Trial 

      Núñez, Julio; Miñana, Gema; Cardells, Ingrid; Palau, Patricia; Llàcer, Pau; Facila Rubio, Lorenzo; Almenar-Bonet, Luis; Lopez-Lereu, Maria Pilar; Monmeneu Menadas, Jose Vicente; Amiguet Comins, Martina; González, Jessika; Serrano, Alicia; Montagud, Vicente; López‐Vilella, Raquel; Valero, Ernesto; García-Blas, Sergio; Bodí, Vicent; de la Espriella-Juan, Rafael; Lupón, Josep; Navarro, Jorge; Górriz, José Luis; Sanchis, Juan American Heart Association (2020-02-13)
      Background Intravenous ferric carboxymaltose (FCM) improves symptoms, functional capacity, and quality of life in heart failure and iron deficiency. The mechanisms underlying these effects are not fully understood. The ...

    • openAccess   Noninvasive ventilation versus conventional oxygen therapy after extubation failure in high-risk patients in an intensive care unit: a pragmatic clinical trial 

      Belenguer-Muncharaz, Alberto; Mateu-Campos, Lidon; Vidal-Tegedor, Bárbara; Ferrándiz Sellés, María de los Desamparados; Micó Gómez, Marisa; Altaba-Tena, Susana; Arlandis-Tomás, María; Álvaro-Sánchez, Rosa; Rodríguez-Martínez, Enver; Rodriguez Portillo, Jairo Associação de Medicina Intensiva Brasileira - AMIB (2021)
      OBJECTIVE: To determine the effectiveness of noninvasive ventilation versus conventional oxygen therapy in patients with acute respiratory failure after extubation failure. METHODS: A pragmatic clinical trial was conducted ...

    • openAccess   Novel sampling strategy for alive animal volatolome extraction combined with GC-MS based untargeted metabolomics: Identifying mouse pup pheromones 

      Lacalle-Bergeron, Leticia; Goterris-Cerisuelo, Rafael; Portoles, Tania; Beltran Arandes, Joaquin; Sancho, Juan V; Navarro-Moreno, Cinta; Martinez-Garcia, Fernando Elsevier (2021-08-04)
      In this study, we identify 11 mouse pup volatiles putatively involved in maternal care induction in adult females. For this purpose, we have adapted the dynamic headspace methodology to extract the volatolome of whole alive ...

    • openAccess   Novel Tissue-Engineered Multimodular Hyaluronic Acid-Polylactic Acid Conduits for the Regeneration of Sciatic Nerve Defect 

      Gisbert Roca, Fernando; Gil Santos, Luis; Mata Roig, Manuel; Milian Medina, Lara; Martínez Ramos, Cristina; Monleón Pradas, Manuel MDPI (2022-05)
      The gold standard for the treatment of peripheral nerve injuries, the autograft, presents several drawbacks, and engineered constructs are currently suitable only for short gaps or small diameter nerves. Here, we study a ...

    • closedAccess   Nucleus incertus ablation disrupted conspecific recognition and modified immediate early gene expression patterns in ‘social brain’ circuits of rats 

      García Díaz, Cristina; Sánchez-Catalán, María José; Castro-Salazar, E.; García Avilés, Álvaro; Albert Gasco, Hector; Sánchez-Sarasúa, Sandra; Sánchez-Pérez, Ana María; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Elsevier (2019-01-01)
      Social interaction involves neural activity in prefrontal cortex, septum, hippocampus, amygdala and hypothalamus. Notably, these areas all receive projections from the nucleus incertus (NI) in the pontine tegmentum. ...