Listar MED_Articles por autoría "6a072b44-0f80-4662-9e38-e40e3ae62f78"

Mostrando ítems 1-7 de 7

    • closedAccess   Chronic Cocaine Effects in Retinal Metabolism and Electrophysiology: Treatment with Topiramate 

      Sánchez-Villarejo, María V.; López-Pedrajas, Rosa; Sánchez Vallejo, Violeta; Genovés, José M.; Muriach Saurí, María; Barcia, Jorge M; Romero, Francisco J. Informa Healthcare (2014)
      Purpose: Cocaine abuse is a major public health problem with multiple-related complications. Indeed, cocaine can affect almost every organ of the human body, but little is known about its effects on the visual system. The ...

    • openAccess   Cocaine promotes oxidative stress and microglial-macrophage activation in rat cerebellum 

      López-Pedrajas, Rosa; Ramírez Lamelas, Dolores T.; Muriach, Borja; Sánchez-Villarejo, María V.; Almansa, Inmaculada; Vidal Gil, Lorena; Romero, Francisco J.; Barcia, Jorge M; Muriach Saurí, María Frontiers Media (2015)
      Different mechanisms have been suggested for cocaine neurotoxicity, including oxidative stress alterations. Nuclear factor kappa B (NF-κB), considered a sensor of oxidative stress and inflammation, is involved in drug ...

    • openAccess   Diabetes and the brain: oxidative stress, inflammation, and autophagy 

      Muriach Saurí, María; Flores-Bellver, Miguel; Romero, Francisco J.; Barcia, Jorge M Hindawi Publishing Corporation (2014)
      Diabetes mellitus is a common metabolic disorder associated with chronic complications including a state of mild to moderate cognitive impairment, in particular psychomotor slowing and reduced mental flexibility, not ...

    • openAccess   Differential hippocampal response to chronic alcohol consumption of young adult and mature adult rats 

      Barcia, Jorge M; Sánchez-Villarejo, María V.; Almansa, Inmaculada; López-Pedrajas, Rosa; Muriach Saurí, María; Romero Gómez, Francisco Javier Oxford University Press (2012-05)
      AIMS Early ethanol consumption could be a risk factor for young brain integrity and its maturation, and also for the development of addictive behaviors in adulthood. Neuronal nitric oxide synthase (nNOS) expressing neurons ...

    • openAccess   Matching Diabetes and Alcoholism: Oxidative Stress, Inflammation, and Neurogenesis Are Commonly Involved 

      Barcia, Jorge M; Flores-Bellver, Miguel; Muriach Saurí, María; Sancho Pelluz, Francisco Javier; Lopez-Malo, Daniel; Urdaneta, Alba C.; Martinez-Gil, Natalia; Atienzar-Aroca, Sandra; Romero, Francisco J. Hindawi Publishing Corporation (2014)
      Diabetes and alcohol misuse are two of the major challenges in health systems worldwide. These two diseases finally affect several organs and systems including the central nervous system. Hippocampus is one of the most ...

    • openAccess   Naltrexone Reverses Ethanol-Induced Rat Hippocampal and Serum Oxidative Damage 

      Almansa, Inmaculada; Barcia, Jorge M; López-Pedrajas, Rosa; Muriach, Maria; Miranda, María; Romero, Francisco J. Hindawi Publishing Corporation (2013)
      Naltrexone, an antagonist of 𝜇�-opioid receptors, is clinically used as adjuvant therapy of alcohol dishabituation. The aim of the present work was to test the effect of 1 mg/kg body weight of naltrexone to revert oxidative ...

    • openAccess   Role of retinal pigment epithelium-derived exosomes and autophagy in new blood vessel formation 

      Atienzar-Aroca, Sandra; Serrano‐Heras, Gemma; Freire Valls, Aida; Ruiz de Almodovar , Carmen; Muriach, Maria; Barcia, Jorge M; García-Verdugo, Jose Manuel; Romero Gómez, Francisco Javier; Sancho Pelluz, Francisco Javier Wiley (2018-08)
      Autophagy and exosome secretion play important roles in a variety of physiological and disease states, including the development of age‐related macular degeneration. Previous studies have demonstrated that these cellular ...