Listar IUPA_Articles por título
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Performance of the linear ion trap Orbitrap mass analyzer for qualitative and quantitative analysis of drugs of abuse and relevant metabolites in sewage water
Elsevier (2013-03-20)This work illustrates the potential of liquid chromatography coupled to a hybrid linear ion trap Fourier Transform Orbitrap mass spectrometer for the simultaneous identification and quantification of 24 drugs of abuse and ... -
Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models
Nature Research (2023)Reversible and sub-lethal stresses to the mitochondria elicit a program of compensatory responses that ultimately improve mitochondrial function, a conserved anti-aging mechanism termed mitohormesis. Here, we show ... -
Perspectives and challenges associated with the determination of new psychoactive substances in urine and wastewater – A tutorial
Elsevier (2021-02-08)New psychoactive substances (NPS), often designed as (legal) substitutes to conventional illicit drugs, are constantly emerging in the drug market and being commercialized in different ways and forms. Their use continues ... -
Pesticide Inhalation Exposure of Applicators and Bystanders Using Conventional and Innovative Cropping Systems in the Valencian Region, Spain
MDPI (2021-05-15)This paper provides scientific results from a European LIFE project carried out in the Valencian region of Spain during the 2017 to 2018 time frame. In 2018, more than 60,000 tons of pesticides were commercialized in Spain, ... -
Pharmaceutical removal from different water matrixes by Fenton process at near-neutral pH: Doehlert design and transformation products identification by UHPLC-QTOF MS using a purpose-built database
Elsevier (2018-08)This work evaluates the Fenton process in the removal of eight pharmaceuticals (gemfibrozil, nimesulide, furosemide, paracetamol, propranolol, dipyrone, fluoxetine, and diazepam), present at an initial concentration of ... -
Pharmaceuticals and environmental risk assessment in municipal wastewater treatment plants and rivers from Peru
Elsevier (2021-06-23)This is the first study dealing with removal of the pharmaceutical substances in municipal wastewater treatment plants (MWWTPs) from Peru and the impact of these compounds in surface waters receiving treated wastewater. ... -
Photo-electro-Fenton process applied to the degradation of valsartan: Effect of parameters, identification of degradation routes and mineralization in combination with a biological system
Elsevier (2018-12)In this work, the oxidation of the antihypertensive drug valsartan by the Electro-Fenton (EF) and photo-electro-Fenton (PEF) processes was studied using a Ti/IrO2 doped with SnO2 as anode, and a carbon felt air diffusion ... -
Potential of atmospheric pressure chemical ionization source in gas chromatography tandem mass spectrometry for the screening of urinary exogenous androgenic anabolic steroids
Elsevier (2016-02-04)The atmospheric pressure chemical ionization (APCI) source for gas chromatography-mass spectrometry analysis has been evaluated for the screening of 16 exogenous androgenic anabolic steroids (AAS) in urine. The sample ... -
Potential of atmospheric pressure chemical ionization source in GC-QTOF MS for pesticide residue analysis
John Wiley & Sons (2010-08)The potential applications of a new atmospheric pressure source for GC-MS analysis have been investigated in this work. A list of around 100 GC-amenable pesticides, which includes organochlorine, organophosphorus and ... -
Potential of gas chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry for screening and quantification of hexabromocyclododecane
Springer (2015)A fast method for the screening and quantification of hexabromocyclododecane (sum of all isomers) by gas chromatography using a triple quadrupole mass spectrometer with atmospheric pressure chemical ionization (GC-APCI-QqQ) ... -
Prediction of Collision Cross-Section Values for Small Molecules: Application to Pesticide Residue Analysis
(2017)The use of collision cross-section (CCS) values obtained by ion mobility high-resolution mass spectrometry has added a third dimension (alongside retention time and exact mass) to aid in the identification of compounds. ... -
Prediction of Retention Time and Collision Cross Section (CCSH+, CCSH–, and CCSNa+) of Emerging Contaminants Using Multiple Adaptive Regression Splines
American Chemical Society (2022-10-24)Ultra-high performance liquid chromatography coupled to ion mobility separation and high-resolution mass spectrometry instruments have proven very valuable for screening of emerging contaminants in the aquatic environment. ... -
Proposal of 5-methoxy-N-methyl-N-isopropyltryptamine consumption biomarkers through identification of in vivo metabolites from mice
Elsevier (2017-07)New psychoactive substances (NPS) are a new breed of synthetically produced substances designed to mimic the effects of traditional illegal drugs. Synthetic cannabinoids and synthetic cathinones are the two most common ... -
Quadrupole-time-of-flight mass spectrometry screening for synthetic cannabinoids in herbal blends
John Wiley & Sons (2013-05)‘Legal highs’ are novel substances which are intended to elicit a psychoactive response. They are sold from ‘head shops’, the internet and from street suppliers and may be possessed without legal restriction. Several months ... -
Qualitative screening of 116 veterinary drugs in feed by liquid chromatography-high resolution mass spectrometry. Potential application to quantitative analysis
Elsevier (2014)Veterinarian and human pharmaceuticals may be intentionally added to animal feed to enhance animal production. Monitoring these substances is necessary for protecting the consumers. In this work, a screening method covering ... -
Qualitative Screening of Undesirable Compounds from Feeds to Fish by Liquid Chromatography Coupled to Mass Spectrometry
American Chemical Society (2013)This paper describes the development, validation, and application of a rapid screening method for the detection and identification of undesirable organic compounds in aquaculture products. A generic sample treatment was ... -
Qualitative validation of a liquid chromatography-quadrupole-time of flight mass spectrometry screening method for organic pollutants in waters
Elsevier (2013-02)A multiclass wide-scope screening of organic contaminants in natural and waste water has been developed and validated for qualitative purposes, i.e. detection and reliable identification of compounds detected in samples ... -
Quality classification of Spanish olive oils by untargeted gas chromatography coupled to hybrid quadrupole–time of flight mass spectrometry with atmospheric pressure chemical ionization and metabolomics-based statistical approach
Elsevier (2017-02)The novel atmospheric pressure chemical ionization (APCI) source has been used in combination with gas chromatography (GC) coupled to hybrid quadrupole time-of-flight (QTOF) mass spectrometry (MS) for determination of ... -
Quantification of prominent volatile compounds responsible for muskmelon and watermelon aroma by purge and trap extraction followed by gas chromatography–mass spectrometry determination
Wiley (2016-01)A dynamic headspace purge-and-trap (DHS-P&T) methodology for the determination and quantification of 61 volatile compounds responsible for muskmelon and watermelon aroma has been developed and validated. The methodology ... -
Quantification, confirmation and screening capability of UHPLC coupled to triple quadrupole and hybrid quadrupole time-of-flight mass spectrometry in pesticide residue analysis
John Wiley & Sons (2010-04)The potential of three mass spectrometry (MS) analyzers (triple quadrupole, QqQ; time of flight, TOF; and quadrupole time of flight, QTOF) has been investigated and compared for quantification, confirmation and screening ...