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dc.contributor.authorHernández Hernández, Félix
dc.contributor.authorBakker, Joost
dc.contributor.authorBijlsma, Lubertus
dc.contributor.authorDe Boer, Jacob H.
dc.contributor.authorBotero-Coy, Ana Maria
dc.contributor.authorBruinen de Bruin, Yuri
dc.contributor.authorFischer, Stellan Taylor
dc.contributor.authorHollender, Juliane
dc.contributor.authorKasprzyk-Hordern, Barbara
dc.contributor.authorLamorée, Marja H.
dc.contributor.authorLópez, F. J.
dc.contributor.authorLaak, Thomas Lter
dc.contributor.authorVan Leerdam, Jan A.
dc.contributor.authorSancho Llopis, Juan Vicente
dc.contributor.authorSchymanski, Emma L.
dc.contributor.authorDe Voogt, Pim W.P.
dc.contributor.authorHogendoorn, Elbert Alex
dc.date.accessioned2019-04-10T08:11:26Z
dc.date.available2019-04-10T08:11:26Z
dc.date.issued2019-05
dc.identifier.citationHERNÁNDEZ, F., et al. The role of analytical chemistry in exposure science: Focus on the aquatic environment. Chemosphere, 2019, vol. 222, p. 564-583ca_CA
dc.identifier.issn0045-6535
dc.identifier.issn1879-1298
dc.identifier.urihttp://hdl.handle.net/10234/182274
dc.description.abstractExposure science, in its broadest sense, studies the interactions between stressors (chemical, biological, and physical agents) and receptors (e.g. humans and other living organisms, and non-living items like buildings), together with the associated pathways and processes potentially leading to negative effects on human health and the environment. The aquatic environment may contain thousands of compounds, many of them still unknown, that can pose a risk to ecosystems and human health. Due to the unquestionable importance of the aquatic environment, one of the main challenges in the field of exposure science is the comprehensive characterization and evaluation of complex environmental mixtures beyond the classical/priority contaminants to new emerging contaminants. The role of advanced analytical chemistry to identify and quantify potential chemical risks, that might cause adverse effects to the aquatic environment, is essential. In this paper, we present the strategies and tools that analytical chemistry has nowadays, focused on chromatography hyphenated to (high-resolution) mass spectrometry because of its relevance in this field. Key issues, such as the application of effect direct analysis to reduce the complexity of the sample, the investigation of the huge number of transformation/degradation products that may be present in the aquatic environment, the analysis of urban wastewater as a source of valuable information on our lifestyle and substances we consumed and/or are exposed to, or the monitoring of drinking water, are discussed in this article. The trends and perspectives for the next few years are also highlighted, when it is expected that new developments and tools will allow a better knowledge of chemical composition in the aquatic environment. This will help regulatory authorities to protect water bodies and to advance towards improved regulations that enable practical and efficient abatements for environmental and public health protection.ca_CA
dc.format.extent20 p.ca_CA
dc.format.mimetypeapplication/pdfca_CA
dc.language.isoengca_CA
dc.publisherElsevierca_CA
dc.relation.isPartOfChemosphere, 2019, vol. 222ca_CA
dc.rights© Elsevier Ltd. All rights reservedca_CA
dc.subjectenvironmental analytical chemistryca_CA
dc.subjectwaterca_CA
dc.subjectexposure scienceca_CA
dc.subjecthigh resolution mass spectrometryca_CA
dc.subjectchromatographyca_CA
dc.subjectemerging contaminantsca_CA
dc.titleThe role of analytical chemistry in exposure science: Focus on the aquatic environmentca_CA
dc.typeinfo:eu-repo/semantics/articleca_CA
dc.identifier.doihttps://doi.org/10.1016/j.chemosphere.2019.01.118
dc.relation.projectIDGeneralitat Valenciana (Group of Excellence Prometeo II): 2014/023; Ministerio Español de Economía y Competitividad: CTQ 2015-65603-P; Ministerio de Educación, Cultura y Deporte: PR 2015-00084; Leverhulme Trust: RPG-2013-297; Natural Environment Research Council: NE/N019261/1; European Commission: 603437; Luxembourg National Research Fund (FNR): 12341006ca_CA
dc.rights.accessRightsinfo:eu-repo/semantics/embargoedAccessca_CA
dc.relation.publisherVersionhttps://www.sciencedirect.com/science/article/pii/S0045653519301225ca_CA
dc.date.embargoEndDate2021-05-01
dc.type.versioninfo:eu-repo/semantics/acceptedVersionca_CA


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