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dc.contributor.authorNegre Gimeno, Patricia
dc.contributor.otherHernández Hernández, Félix
dc.contributor.otherUniversitat Jaume I. Departament de Química Física i Analítica
dc.date.accessioned2018-03-29T11:57:05Z
dc.date.available2018-03-29T11:57:05Z
dc.date.issued2017
dc.identifier.urihttp://hdl.handle.net/10234/173882
dc.descriptionTreball Final de Grau en Química. Codi: QU0943. Curs acadèmic: 2016/2017ca_CA
dc.description.abstractIn the past decades, drugs of abuse (DOAS) have been widely consumed in Europe. Most of these drugs are illegal, and their consumption is forbidden. This has led to the increase use of new psychoactive substances (NPS), developed to try to evade the law and commonly known as “legal highs”. NPS market is continuously changing to develop new substances to replace those that are banned. Detection and identification of NPS is an analytical challenge due to the continuous changes in production and quick distribution. The analysis of NPS in this work has been performed with the application of ultra-high performance liquid chromatography (UHPLC) coupled to high resolution mass spectrometry with an hybrid quadrupole time-of-flight mass analyser (QTOF MS) with electrospray ionization (ESI). The accurate mass full-spectra acquisition data provided by QTOF MS has allowed a reliable identification of the compounds of interest, even if reference standards are not available. Twelve urine samples were analyzed and two databases were used to detect and identify the NPS and DOAS in the samples.ca_CA
dc.format.extent28 p.ca_CA
dc.format.mimetypeapplication/pdfca_CA
dc.language.isoengca_CA
dc.publisherUniversitat Jaume Ica_CA
dc.rights.urihttp://rightsstatements.org/vocab/CNE/1.0/*
dc.subjectGrau en Químicaca_CA
dc.subjectGrado en Químicaca_CA
dc.subjectBachelor's Degree in Chemistryca_CA
dc.titleScreening of drugs of abuse and new psychoactive substances in biological human samplesca_CA
dc.typeinfo:eu-repo/semantics/bachelorThesisca_CA
dc.educationLevelEstudios de Gradoca_CA
dc.rights.accessRightsinfo:eu-repo/semantics/restrictedAccessca_CA


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