Show simple item record

dc.contributor.authorArnau del Valle, Carla
dc.contributor.otherGalindo Honrubia, Francisco
dc.contributor.otherUniversitat Jaume I. Departament de Química Inorgànica i Orgànica
dc.date.accessioned2018-03-28T07:23:46Z
dc.date.available2018-03-28T07:23:46Z
dc.date.issued2016
dc.identifier.urihttp://hdl.handle.net/10234/173791
dc.descriptionTreball Final del Màster Universitari en Química Aplicada i Farmacològica. Codi: SIM138. Curs acadèmic 2016/2017ca_CA
dc.description.abstractResistance to antibiotics by microorganism has increased in the last decades. Due to the increased resistance, it is very important to look for alternative ways to fight bacterial infections. Almost all microorganisms can form biofilm on a wide range of surfaces i.e. biological and inert ones. Biofilm presence causes a great problem for public health due to its resistant nature to antibiotics and disease associated with indwelling medical devices (for instance, catheters). Biofilm forming capability has been reported in large number of bacterial species such as P. aeruginosa, S. epidermidis, E. coli spp, S. aureus, E. cloacae and K. pneumonia.[1] It has been estimated that healthcare associated infections cause 37,000 deaths in Europe every year, with an economic burden of €13 - 24 billion.[2] In the United States, the estimated death toll is about 99,000 every year, with an economic cost of $33 billion.[3] Although the general public is becoming slowly aware of this global threat, public institutions have been warning since long time ago about the imminent crisis on this regard. The problem could reach in the future unprecedented proportions since microbial resistance has been recently described both as a ‘One Health Issue’ and as a ‘One World Issue’.[4] Therefore, the search for new techniques to reduce bacterial infections is of vital importance. Increasing attention is currently devoted to the development of surfaces disfavouring the adhesion of bacteria and hence impeding the formation of biofilms. One of the strategies consists in the use of cationic groups able to disrupt the membrane of the microorganism (alkylamonium, phosphonium, sulfonium, etc). Anhother strategy to fight bacterial infections is the antimicrobial photodynamic therapy (aPDT).ca_CA
dc.format.extent74 p.ca_CA
dc.format.mimetypeapplication/pdfca_CA
dc.language.isoengca_CA
dc.publisherUniversitat Jaume Ica_CA
dc.subjectMàster Universitari en Química Aplicada i Farmacològicaca_CA
dc.subjectMáster Universitario en Química Aplicada y Farmacológicaca_CA
dc.subjectMaster's Degree in Applied and Pharmacology Chemistryca_CA
dc.subjectcationic polymersca_CA
dc.subjectphotodynamic therapyca_CA
dc.titleStudy of cationic polymers as supports for photosensitizers with application in photodynamic therapyca_CA
dc.typeinfo:eu-repo/semantics/masterThesisca_CA
dc.educationLevelEstudios de Postgradoca_CA
dc.rights.accessRightsinfo:eu-repo/semantics/restrictedAccessca_CA


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record