Synthesis of Inhibitors of Cysteine Protease
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Metadatos
Título
Synthesis of Inhibitors of Cysteine ProteaseAutoría
Tutor/Supervisor; Universidad.Departamento
González Adelantado, Florenci VicentFecha de publicación
2017-07-14Editor
Universitat Jaume IResumen
Protozoa which cause diseases such as Malaria, Chagas’ disease or Sleeping sickness contains cysteine proteases. These enzymes are important in the cycle life of parasites. Inhibitors of cysteine proteases represent ... [+]
Protozoa which cause diseases such as Malaria, Chagas’ disease or Sleeping sickness contains cysteine proteases. These enzymes are important in the cycle life of parasites. Inhibitors of cysteine proteases represent a way to find new drugs against these tropical infectious diseases.
Lately, several inhibitors for this type of proteases were developed. In this work, a dipeptidyl nitrolkene has been synthetized, with a new modification in the chemical structure: isonicotinyl as a protecting group. This compound is expected to display a high inhibition activity against cysteine proteases. [-]
Palabras clave / Materias
Descripción
Treball Final de Grau en Química. Codi: QU0943
Tipo de documento
info:eu-repo/semantics/bachelorThesisDerechos de acceso
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- Grau en Química [265]