Synthetic Derivatizations of Activated Epoxides

Abstract

In the past, diseases were cured with natural compounds from plants, but today, almost all diseases like a headache or to treat a cancer are made by drugs synthesized from those compounds that came from nature. There are a wide variety of drugs, so we will only focus on no- steroidal drugs that are used as an anti-inflammatory drugs, such as ibuprofen, naproxen, etc. In this work we will try to deepen in the obtaining some of these non-steroidal drugs from epoxysulfones, which are important building block in the organic chemistry due to their reactivity. Therefore, we want to obtain this type of drugs enantioselectively, with few steps and with a green chemistry