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dc.contributor.authorCuerda, María Cristina
dc.contributor.authorApezetxea, Antonio
dc.contributor.authorCarrillo, Lourdes
dc.contributor.authorCasanueva, Felipe
dc.contributor.authorCuesta, Federico
dc.contributor.authorIrles, José Antonio
dc.contributor.authorLayola, Miquel
dc.contributor.authorLizán, Luis
dc.date.accessioned2017-02-01T13:55:18Z
dc.date.available2017-02-01T13:55:18Z
dc.date.issued2016-07
dc.identifier.citationCUERDA, Maria Cristina, et al. Reliability and Responsiveness of NutriQoL® Questionnaire. Advances in therapy, 2016, vol. 33, no 10, p. 1728-1739.ca_CA
dc.identifier.urihttp://hdl.handle.net/10234/165796
dc.description.abstractIntroduction NutriQoL® (Nestlé Health Science, Vevay, Switzerland) is a questionnaire developed to assess the health-related quality-of-life (HRQoL) of patients with home enteral nutrition (HEN) irrespective of their underlying condition and route of administration. The aim of this work is assessing the questionnaire’s reliability and responsiveness to change. Methods Two cohorts of patients with HEN and their primary caregivers were enrolled to assess reliability and responsiveness, respectively. All participants had to be 18 years of age or older, without mental deterioration (≤3 or 4 errors in the Pfeiffer’s test) and with sufficient functional status (>40 points on Karnovsky’s performance status scale). When the patients’ ability to respond to the questionnaire was impaired due to underlying disease, their caregivers answered on their behalf. NutriQoL was administered in two and three visits to reliability and responsiveness cohorts, respectively. Test–retest reliability and internal consistency were assessed by the intra-class correlation coefficient (ICC) and the Cronbach’s α, respectively. Responsiveness was evaluated by standardized effect size and standardized response mean between basal visit and third visit. Finally, the minimal clinically important difference (MCID) was estimated. Results A total of 54 and 86 participants were recruited to the reliability and responsiveness cohort, respectively. Thirty-five caregivers were selected to assess the inter-observer reliability. ICC values confirmed the good reproducibility level (ICC >0.75) of the questionnaire in both “physical functioning and activities of daily living” and “social life” domains and total score. The assessment of internal consistency in both domains of the questionnaire showed good internal consistency in visit 2. ICC showed the excellent agreement level between caregiver and patient in the global NutriQoL score. Finally, patients classified as having a minimal change in their health reported a mean (standard deviation) MCID in NutriQoL score of 0.63 (11.51). Conclusion NutriQoL is a reliable and unique instrument to measure the HRQoL in HEN patients. NutriQoL detects changes in the health status of the patient. Nevertheless, further research is needed to determine the full extent of the questionnaire responsiveness.ca_CA
dc.description.sponsorShipSponsorship and article processing charges for this study were funded by Nestlé Health Science, Barcelona, Spain. Medical writing assistance for this study was provided by Outcomes’10, Castellón de la Plana, Spain, and funded by Nestlé Health Science, Barcelona, Spain. All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this manuscript, take responsibility for the integrity of the work as a whole, and have given final approval for the version to be published.ca_CA
dc.format.extent11 p.ca_CA
dc.format.mimetypeapplication/pdfca_CA
dc.language.isoengca_CA
dc.publisherSpringer Verlagca_CA
dc.relation.isPartOfAdvances in Therapy October 2016, Volume 33, Issue 10ca_CA
dc.rights© 2017 Springer International Publishing AG. Part of Springer Nature.ca_CA
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/*
dc.subjectGastroenterologyca_CA
dc.subjectHealth-related quality-of-lifeca_CA
dc.subjectHome enteral nutritionca_CA
dc.subjectReliabilityca_CA
dc.subjectResponsivenessca_CA
dc.titleReliability and Responsiveness of NutriQoL® Questionnaireca_CA
dc.typeinfo:eu-repo/semantics/articleca_CA
dc.identifier.doihttp://dx.doi.org/10.1007/s12325-016-0384-8
dc.rights.accessRightsinfo:eu-repo/semantics/restrictedAccessca_CA
dc.relation.publisherVersionhttp://link.springer.com/article/10.1007/s12325-016-0384-8#enumerationca_CA
dc.type.versioninfo:eu-repo/semantics/publishedVersion


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