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Oxygen transport through methacrylate-based hydrogels with potential biological capability
dc.contributor.author | Compañ, Vicente | |
dc.contributor.author | San Román, Julio | |
dc.contributor.author | Riande, Evaristo | |
dc.contributor.author | Smith Sorensen, T. | |
dc.contributor.author | Levenfeld, B. | |
dc.contributor.author | Andrio, Andreu | |
dc.date.accessioned | 2016-12-20T13:22:30Z | |
dc.date.available | 2016-12-20T13:22:30Z | |
dc.date.issued | 1996 | |
dc.identifier.issn | 0142-9612 | |
dc.identifier.issn | 1878-5905 | |
dc.identifier.uri | http://hdl.handle.net/10234/165128 | |
dc.description.abstract | The permeability to oxygen of hydrogels prepared from copolymers of 2-hydroxymethyl methacrylate and p-methacryloxyl-oxyacetanilide have been studied by using an oxygen electrode in combination with a permeometer. The transmissibility Full-size image (<1 K) and the permeability Dk (where D, k and L are, respectively, the diffusion coefficient, the Henry constant and the thickness of the hydrogel) are measured by a combination of steady state and transitory state measurements. Both transport coefficients increase with the water content, which in turn depends on the copolymer composition. The values of these quantities tend toward a limiting value for water-saturated hydrogels. The ratio of the characteristic volume for diffusion of the oxygen molecule to the free volume of water per mole water is found to be in the vicinity of 0.10, and this value increases slightly as the fraction of the hydrophilic comonomer in the hydrogel increases. A detailed comparison of the biogels studied with six commercial contact lenses has also been performed. | ca_CA |
dc.description.sponsorShip | The authors are grateful for the financial support provided from the Comision Interministerial de Ciencia y Tecnologia, DGICYT (Ministry of Education and Science of Spain) under project PB92-077%COS-03. One of the authors, Torben Smith Sorensen, is indebted to the Conselleria Educaci6 i Ciencia, Generalitat Valenciana, for a grant for staying at the Universitat Jaume I, Castellon, Spain. We also wish to express our gratitude to Wohlk, D2314 Schiinkirchen, Germany, for providing specimens of commercial contact lenses. | ca_CA |
dc.format.extent | 7 p. | ca_CA |
dc.language.iso | eng | ca_CA |
dc.publisher | Elsevier | ca_CA |
dc.relation.isPartOf | Biomoterials 17 (1996) 1243-1249 | ca_CA |
dc.rights | © 1996 Elsevier Science Limited Printed in Great Britain. All rights reserved | ca_CA |
dc.rights.uri | http://rightsstatements.org/vocab/InC/1.0/ | * |
dc.subject | Hydrogels | ca_CA |
dc.subject | contact lenses | ca_CA |
dc.subject | oxygen transport | ca_CA |
dc.subject | permeability | ca_CA |
dc.subject | pharmacological capability | ca_CA |
dc.title | Oxygen transport through methacrylate-based hydrogels with potential biological capability | ca_CA |
dc.type | info:eu-repo/semantics/article | ca_CA |
dc.identifier.doi | http://dx.doi.org/10.1016/0142-9612(96)84945-3 | |
dc.rights.accessRights | info:eu-repo/semantics/restrictedAccess | ca_CA |
dc.relation.publisherVersion | http://www.sciencedirect.com/science/article/pii/0142961296849453 | ca_CA |
dc.type.version | info:eu-repo/semantics/publishedVersion |
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