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Nitric oxide sensitive fluorescent polymeric hydrogels showing negligible interference by dehydroascorbic acid
dc.contributor.author | Fabregat Tena, Víctor | |
dc.contributor.author | Izquierdo Arcusa, María Ángeles | |
dc.contributor.author | Burguete, M. Isabel | |
dc.contributor.author | Galindo, Francisco | |
dc.contributor.author | Luis, Santiago V. | |
dc.date.accessioned | 2015-07-30T09:30:18Z | |
dc.date.available | 2015-07-30T09:30:18Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 0014-3057 | |
dc.identifier.uri | http://hdl.handle.net/10234/129666 | |
dc.description.abstract | A series of nitric oxide (NO) sensitive polymeric hydrogels have been synthesized and their properties described. The new materials are based on a poly(2-hydroxyethyl methacrylate) matrix entrapping the DAF-FM (4-amino-5-methylamino-2′,7′-difluorofluorescein) fluorescent probe. Some of the developed materials show sensitivities in the range ca. 50–75 nM towards NO dissolved in aerated phosphate buffer (PBS), being nitrous anhydride the reactive species under such conditions. Remarkably, the sensitivity of the fluorescent polymers is not influenced by dehydroascorbic acid, a molecule of biological importance, which has been reported to be a common interfering species capable to react with well known probes for NO. | ca_CA |
dc.format.mimetype | application/pdf | ca_CA |
dc.language.iso | eng | ca_CA |
dc.publisher | Elsevier | ca_CA |
dc.relation.isPartOf | European Polymer Journal, 2014, vol. 55 | ca_CA |
dc.rights.uri | http://rightsstatements.org/vocab/CNE/1.0/ | * |
dc.subject | nitric oxide | ca_CA |
dc.subject | fluorescence sensing | ca_CA |
dc.subject | probes | ca_CA |
dc.subject | dehydroascorbic acid | ca_CA |
dc.subject | polymeric hydrogels | ca_CA |
dc.title | Nitric oxide sensitive fluorescent polymeric hydrogels showing negligible interference by dehydroascorbic acid | ca_CA |
dc.type | info:eu-repo/semantics/article | ca_CA |
dc.identifier.doi | http://dx.doi.org/10.1016/j.eurpolymj.2014.03.027 | |
dc.rights.accessRights | info:eu-repo/semantics/restrictedAccess | ca_CA |
dc.relation.publisherVersion | http://www.sciencedirect.com/science/article/pii/S0014305714001074 | ca_CA |
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