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dc.contributor.authorFabregat Tena, Víctor
dc.contributor.authorIzquierdo Arcusa, María Ángeles
dc.contributor.authorBurguete, M. Isabel
dc.contributor.authorGalindo, Francisco
dc.contributor.authorLuis, Santiago V.
dc.date.accessioned2015-07-30T09:30:18Z
dc.date.available2015-07-30T09:30:18Z
dc.date.issued2014
dc.identifier.issn0014-3057
dc.identifier.urihttp://hdl.handle.net/10234/129666
dc.description.abstractA series of nitric oxide (NO) sensitive polymeric hydrogels have been synthesized and their properties described. The new materials are based on a poly(2-hydroxyethyl methacrylate) matrix entrapping the DAF-FM (4-amino-5-methylamino-2′,7′-difluorofluorescein) fluorescent probe. Some of the developed materials show sensitivities in the range ca. 50–75 nM towards NO dissolved in aerated phosphate buffer (PBS), being nitrous anhydride the reactive species under such conditions. Remarkably, the sensitivity of the fluorescent polymers is not influenced by dehydroascorbic acid, a molecule of biological importance, which has been reported to be a common interfering species capable to react with well known probes for NO.ca_CA
dc.format.mimetypeapplication/pdfca_CA
dc.language.isoengca_CA
dc.publisherElsevierca_CA
dc.relation.isPartOfEuropean Polymer Journal, 2014, vol. 55ca_CA
dc.rights.urihttp://rightsstatements.org/vocab/CNE/1.0/*
dc.subjectnitric oxideca_CA
dc.subjectfluorescence sensingca_CA
dc.subjectprobesca_CA
dc.subjectdehydroascorbic acidca_CA
dc.subjectpolymeric hydrogelsca_CA
dc.titleNitric oxide sensitive fluorescent polymeric hydrogels showing negligible interference by dehydroascorbic acidca_CA
dc.typeinfo:eu-repo/semantics/articleca_CA
dc.identifier.doihttp://dx.doi.org/10.1016/j.eurpolymj.2014.03.027
dc.rights.accessRightsinfo:eu-repo/semantics/restrictedAccessca_CA
dc.relation.publisherVersionhttp://www.sciencedirect.com/science/article/pii/S0014305714001074ca_CA


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