Co-assembly of tetrapeptides into complex pH-responsive molecular hydrogel networks
Visualitza/
Impacte
Scholar |
Altres documents de l'autoria: Tena Solsona, Marta; Alonso de Castro, S.; Miravet, Juan; Escuder, Beatriu
Metadades
Mostra el registre complet de l'elementcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/7053
comunitat-uji-handle3:10234/8639
comunitat-uji-handle4:
INVESTIGACIONMetadades
Títol
Co-assembly of tetrapeptides into complex pH-responsive molecular hydrogel networksData de publicació
2014-07Editor
Royal Society of ChemistryCita bibliogràfica
TENA-SOLSONA, M., et al. Co-assembly of tetrapeptides into complex pH-responsive molecular hydrogel networks. Journal of Materials Chemistry B, 2014, 2.37: 6192-6197.Tipus de document
info:eu-repo/semantics/articleVersió de l'editorial
http://pubs.rsc.org/en/Content/ArticleLanding/2014/TB/C4TB00795F#!divAbstractParaules clau / Matèries
Resum
Here we prepare pH-responsive complex molecular hydrogels from oppositely charged tetrapeptidic components that can be pH-tuned resulting in interconversion between different networks. Two different systems are described ... [+]
Here we prepare pH-responsive complex molecular hydrogels from oppositely charged tetrapeptidic components that can be pH-tuned resulting in interconversion between different networks. Two different systems are described based on tetrapeptides with an alternating sequence of non-polar (F) and polar (D or K) residues. Co-aggregated hydrogels are easily formed in situ at neutral pH whereas one-component networks are maintained after changing into acidic or basic pH. These systems have been applied for the pH selective release of two hydrophobic dyes – Methylene Blue and Bromothymol Blue – as drug models. Different release profiles have been observed depending on the characteristics of the network as well as the pH of the media. These materials offer great potential as multidrug carriers. [-]
Publicat a
Journal of Materials Chemistry B, 2014, 2.37Drets d'accés
© The Royal Society of Chemistry 2014
http://rightsstatements.org/vocab/InC/1.0/
info:eu-repo/semantics/openAccess
http://rightsstatements.org/vocab/InC/1.0/
info:eu-repo/semantics/openAccess
Apareix a les col.leccions
- QUIO_Articles [689]