http://repositori.uji.es:80/xmlui The DSpace digital repository system captures, stores, indexes, preserves, and distributes digital research material. Tue, 21 May 2013 03:40:45 GMT 2013-05-21T03:40:45Z http://hdl.handle.net/10234/64050 Chulvi Ramos, Vicente; Mulet Escrig, Elena; Chakrabarti, Amaresh; López Mesa, Belinda; González-Cruz, Carmen This work analyses the influence of several design methods on the degree of creativity of the design outcome. A design experiment has been carried out in which the participants were divided into four teams of three members, and each team was asked to work applying different design methods. The selected methods were Brainstorming, Functional Analysis, and SCAMPER method. The ‘degree of creativity’ of each design outcome is assessed by means of a questionnaire offered to a number of experts and by means of three different metrics: the metric of Moss, the metric of Sarkar and Chakrabarti, and the evaluation of innovative potential. The three metrics share the property of measuring the creativity as a combination of the degree of novelty and the degree of usefulness. The results show that Brainstorming provides more creative outcomes than when no method is applied, while this is not proved for SCAMPER and Functional Analysis. Mon, 20 May 2013 13:56:34 GMT http://hdl.handle.net/10234/64050 2013-05-20T13:56:34Z Chulvi Ramos, Vicente Mulet Escrig, Elena Chakrabarti, Amaresh López Mesa, Belinda González-Cruz, Carmen http://hdl.handle.net/10234/64036 Camacho Cuena, Eva; Requate, Till Many environmental problems, notably arising from agriculture, can be classified as non-point source pollution problems. In this paper we present results of an experimental study on the performance of three mechanisms designed to deal with such problems: collective fining, random fining, and a tax-subsidy scheme. We find that the fining schemes induce under-abatement, a feature being enforced with experience. We further elicit the participants' risk attitude and show that the performance of collective fining is not affected by the subjects' risk preferences. Under a system based on random fining the performance of the mechanism worsens in the presence of risk seeking subjects. However, coordination on over-abatement under the tax-subsidy can be alleviated if subjects are risk averse Fri, 17 May 2013 19:01:45 GMT http://hdl.handle.net/10234/64036 2013-05-17T19:01:45Z Camacho Cuena, Eva Requate, Till http://hdl.handle.net/10234/64035 Ledesma Llorente, Juan Carlos; González Aragón, Carlos; Font Hurtado, Laura Background In the brain, the enzyme catalase by reacting with H2O2 forms Compound I (catalase–H2O2 system), which is the main system of central ethanol metabolism to acetaldehyde. Previous research has demonstrated that acetaldehyde derived from central-ethanol metabolism mediates some of the psychopharmacological effects produced by ethanol. Manipulations that modulate central catalase activity or sequester acetaldehyde after ethanol administration modify the stimulant effects induced by ethanol in mice. However, the role of H2O2 in the behavioral effects caused by ethanol has not been clearly addressed. The present study investigated the effects of ebselen, an H2O2 scavenger, on ethanol-induced locomotion. Methods Swiss RjOrl mice were pre-treated with ebselen (0–50 mg/kg) intraperitoneally (IP) prior to administration of ethanol (0–3.75 g/kg; IP). In another experiment, animals were pre-treated with ebselen (0 or 25 mg/kg; IP) before caffeine (15 mg/kg; IP), amphetamine (2 mg/kg; IP) or cocaine (10 mg/kg; IP) administration. Following these treatments, animals were placed in an open field to measure their locomotor activity. Additionally, we evaluated the effect of ebselen on the H2O2-mediated inactivation of brain catalase activity by 3-amino-1,2,4-triazole (AT). Results Ebselen selectively prevented ethanol-induced locomotor stimulation without altering the baseline activity or the locomotor stimulating effects caused by caffeine, amphetamine and cocaine. Ebselen reduced the ability of AT to inhibit brain catalase activity. Conclusions Taken together, these data suggest that a decline in H2O2 levels might result in a reduction of the ethanol locomotor-stimulating effects, indicating a possible role for H2O2 in some of the psychopharmacological effects produced by ethanol Fri, 17 May 2013 18:31:33 GMT http://hdl.handle.net/10234/64035 2013-05-17T18:31:33Z Ledesma Llorente, Juan Carlos González Aragón, Carlos Font Hurtado, Laura http://hdl.handle.net/10234/64034 Roca, Maite; Aranda, Juan; Moliner Ibáñez, Vicent; Tuñón, Iñaki Biological catalysis is a complex chemical process that involves not only electronic reorganization in the substrate but also the reorganization of the catalyst. This complexity is even larger in the case of post-transcriptional and post-translational modifications which may involve the interaction between two biomacromolecules. However, the development over the past decades of new computational methods and strategies is offering a detailed molecular picture of the catalytic event and a deep understanding of the mechanisms of chemical reactions in biological environments. Here we review the efforts made in the last years to model catalysis in post-transcriptional and post-translational processes. We stress on the advantages and problems of the different computational strategies and their applicability in different cases Fri, 17 May 2013 17:36:14 GMT http://hdl.handle.net/10234/64034 2013-05-17T17:36:14Z Roca, Maite Aranda, Juan Moliner Ibáñez, Vicent Tuñón, Iñaki http://hdl.handle.net/10234/64033 Mateu, Jorge This short paper introduces the special issue containing six selected papers coming from the International Workshop on Spatio-temporal Modeling (METMA V) held in San- tiago de Compostela (Spain), from 30 June to 2 July 2010. Fri, 17 May 2013 17:07:26 GMT http://hdl.handle.net/10234/64033 2013-05-17T17:07:26Z Mateu, Jorge http://hdl.handle.net/10234/64032 Sáez, M.; Barceló, M.A.; Tobias, A.; Varga, D.; Ocaña-Riola, R.; Juan, P.; Mateu, J. We propose a model to describe the mean function as well as the spatio-temporal covariance structure of 15 years of both maximum and minimum daily temperature data from 190 stations throughout the region of Catalonia (Spain), with daily data covering the period 1994-2008. Our aim is threefold: (a) estimation of the long-term trend of maximum and minimum temperatures; (b) assessing the spatial and temporal variability of temperatures, and (c) interpolation of the spatial temperatures at any given time. Long-term trend, annual harmonics and winds were considered as explanatory vari- ables of the mean function. The parameters associated with these variables were allowed to vary between stations and within each year. We controlled temporal autocorrelation by means of ARMA models. For the spatial covariance structure we used the Mat ern family of covariance functions and a nugget term. Spatio-temporal models were built as Bayesian hierarchical models with two stages following the integrated nested place Laplace approximation (INLA) for Bayesian inference. For the nal model estimation we used a two-stage approach, in which we rst assumed the stations were spatially independent, and then we modeled the spatio-temporal covariance using the interim posterior from the residuals of the model in the rst-stage as prior distributions of replications of a spatial process. We allowed all spatial parameters to also vary with time. Fri, 17 May 2013 16:22:03 GMT http://hdl.handle.net/10234/64032 2013-05-17T16:22:03Z Sáez, M. Barceló, M.A. Tobias, A. Varga, D. Ocaña-Riola, R. Juan, P. Mateu, J. http://hdl.handle.net/10234/64031 Molina Morales, Francesc Xavier; Capó Vicedo, Josep; Tomás Miquel, José V.; Expósito Langa, Manuel Las empresas pertenecientes a aglomeraciones territoriales como un distrito industrial establecen una serie de interdependencias ente ellas que les generan diversos beneficios, como es el caso del acceso a recursos compartidos. Las redes sociales se han utilizado para representar estas interacciones en las que las empresas e instituciones se encuentran inmersas. Sin embargo, las empresas establecen diferentes redes atendiendo a los propósitos estratégicos que traten de cubrir. En nuestro trabajo hemos identificado la presencia de 2 tipos diferentes de redes relacionales: la red de negocio y la red de conocimiento, y mostramos cómo estas 2 redes son significativamente distintas en su caracterización estructural, en términos de densidad, rango, cercanía o intermediación. Por otro lado, las 2 redes presentan efectos diferenciados en la densidad y abundancia de nodos. Estos resultados permiten una mejor compresión de la heterogeneidad interna de estas redes territoriales y sugieren una serie de implicaciones tanto para el mundo académico como para la práctica empresarial.; Firms belonging to territorial agglomerations such as industrial districts, establish a number of interdependences among them, which provide diverse benefits as access to shared resources. Social networks have been used to represent these interactions in which firms and institutions are embedded. However, firms establish different networks according to the different strategic objectives to be covered. Our study shows the existence of two different types of relational networks: the business network and the knowledge network. This work proves how both networks are significantly different in structural characteristics in terms of density, closeness or intermediation. On the other hand, these networks provide differentiated effects in density and abundance of nodes. These findings offer a better understanding of the internal heterogeneity of these territorial networks and suggest a number of implications for both future research and practitioners. Fri, 17 May 2013 15:23:56 GMT http://hdl.handle.net/10234/64031 2013-05-17T15:23:56Z Molina Morales, Francesc Xavier Capó Vicedo, Josep Tomás Miquel, José V. Expósito Langa, Manuel http://hdl.handle.net/10234/64030 Vindel Cañas, Purificación; Campos Sancho, Beatriz In this paper we find topological conditions for the non existence of heteroclinic trajectories connecting saddle orbits in non singular Morse-Smale flows on S 3 . We obtain the non singular Morse-Smale flows that can be decomposed as connected sum of flows and we show that these flows are those who have no heteroclinic trajectories connecting saddle orbits. Moreover, we characterize these flows in terms of links of periodic orbits. Fri, 17 May 2013 13:38:34 GMT http://hdl.handle.net/10234/64030 2013-05-17T13:38:34Z Vindel Cañas, Purificación Campos Sancho, Beatriz http://hdl.handle.net/10234/63943 Anònim Reliquia de les tisores i el mocador de Sant Pasqual Fri, 17 May 2013 11:05:17 GMT http://hdl.handle.net/10234/63943 2013-05-17T11:05:17Z Anònim http://hdl.handle.net/10234/63942 Desconocido José Manuel Barroso, President of the EC, participated in the celebration of the 25th anniversary of the accession of Spain and Portugal to the EU. The Spanish Royal Family, Jerzy Buzek, President of the EP, José Socrates, Portuguese Prime Minister, and José Luis Rodriguez Zapatero, Spanish Prime Minister also attended the ceremony in MadridLetizia, Princess of Asturias, Felipe, Prince of Asturias, Sofia, Queen of Spain, Juan Carlos, King of Spain, seated from left to right, and José Manuel Barroso, at the podium Fri, 17 May 2013 11:02:44 GMT http://hdl.handle.net/10234/63942 2013-05-17T11:02:44Z Desconocido