Listar por tema "SARS-CoV"

Mostrando ítems 1-3 de 3

    • openAccess   Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis 

      Castaño Rodríguez, Carlos; Honrubia, José M.; Gutiérrez-Álvarez, Javier; De Diego, Marta L.; Nieto Torres, José L.; Jiménez Guardeño, José M.; Regla Nava, José A.; Fernández Delgado, Raúl; Verdiá Báguena, Carmen; Queralt-Martín, María; Kochan, Grazyna; Perlman, Stanley; Aguilella, Vicente; Sola, Isabel; Enjuanes, Luis American Society for Microbiology (2018)
      Viroporins are viral proteins with ion channel (IC) activity that play an important role in several processes, including virus replication and pathogenesis. While many coronaviruses (CoVs) encode two viroporins, severe ...

    • openAccess   Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome 

      Nieto Torres, José L.; Verdiá Báguena, Carmen; Jiménez Guardeño, José M.; Regla Nava, José A.; Castaño Rodríguez, Carlos; Fernández Delgado, Raúl; Torres, Jaume; Aguilella, Vicente; Enjuanes, Luis Elsevier (2015-11)
      Severe acute respiratory syndrome coronavirus (SARS-CoV) envelope (E) protein is a viroporin involved in virulence. E protein ion channel (IC) activity is specifically correlated with enhanced pulmonary damage, edema ...

    • openAccess   The Complex Proteolipidic Behavior of the SARS-CoV-2 Envelope Protein Channel: Weak Selectivity and Heterogeneous Oligomerization 

      Surya, Wahyu; Tavares Neto, Ernesto; Sanchis, Andrea; Queralt-Martín, María; Alcaraz, Antonio; Torres, Jaume; Aguilella, Vicente Multidisciplinary Digital Publishing Institute (MDPI) (2023-08-05)
      The envelope (E) protein is a small polypeptide that can form ion channels in coronaviruses. In SARS coronavirus 2 (SARS-CoV-2), the agent that caused the recent COVID-19 pandemic, and its predecessor SARS-CoV-1, E protein ...