Listar por tema "Enzimas"
Mostrando ítems 1-3 de 3
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Quantum Mechanics/Molecular Mechanics modeling of biological relevant reactions catalyzed by enzymes
Universitat Jaume I (2017-09-28)A theoretical study of the hydrolysis of a β-lactam antibiotic was carried out in gas phase at different levels of theory. Later, the reaction was studied in solution, describing the sub-set of atoms of the QM region with ... -
Síntesis de análogos nucleosídicos por desaminación biocatalítica
Universitat Jaume I (2023-01-19)En aquest treball s'ha produït un enzim de manera recombinant amb capacitat de desaminar una posició concreta d'un anàleg nucleosídic d'interés comercial. Aquest enzim ha estat caracteritzat i emprat en l'optimització d'una ... -
Synthesis of cysteine protease inhibitors through Darzens reactions
Universitat Jaume I (2014)In this work, we are going to talk about the cysteine proteases. In the cysteine proteases, or thiol proteases, the mechanism involves a nucleophilic thiol in a catalytic triad or dyad. Cysteine proteases are common in ...