Listar por tema "Docking"

Mostrando ítems 1-2 de 2

    • openAccess   Novel multitarget inhibitors with antiangiogenic and immunomodulator properties 

      Conesa Milián, Laura; Falomir, Eva; Murga, Juan; Carda, Miguel; Marco, J. Alberto Elsevier (2019-03-08)
      By means of docking studies, seventeen compounds T.1-T17 have been designed and evaluated as multitarget inhibitors of VEGFR-2 and PD-L1 proteins in order to overcome resistance phenomena offered by cancer. All these ...

    • openAccess   Understanding Acetylcholinesterase Inhibitors: Computational Modeling Approaches 

      Moreno Nascimento, Érica Cristina Universitat Jaume I (2017-07-25)
      La presente Tesis Doctoral constituye un estudio teórico sobre el proceso de inhibición de la acetilcolinesterasa por moléculas que bloquean el sitio activo de la proteína. Se han estudiado un conjunto de 44 inhibidores, ...