Listar por tema "Citotoxicitat"
Mostrando ítems 1-2 de 2
-
Design and synthesis of pironetin analogues with simplified structure and study of their interactions with microtubules
Elsevier (2011-05)The preparation of a series of pironetin analogues with simplified structure is described. Their cytotoxic activity and their interactions with tubulin have been investigated. It has been found that, while less active than ... -
Synthesis and biological properties of the cytotoxic 14-membered macrolides aspergillide A and B
Wiley (2010-11-09)Total, stereoselective syntheses of the naturally occurring, cytotoxic macrolides aspergillide A and B are described. Olefin metatheses and asymmetric allylations were key steps in the synthetic sequences. Cytotoxicity ...