Listar por tema "Catalase"
Mostrando ítems 1-9 de 9
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Alpha-lipoic acid, a scavenging agent for H2O2, reduces ethanol-stimulated locomotion in mice
Springer-Verlag (2011-07-19)Rationale The main system of central ethanol oxidation is mediated by the enzyme catalase. By reacting with H2O2, brain catalase forms compound I (the catalase–H2O2 system), which is able to oxidize ethanol to acetaldehyde ... -
Infusions of acetaldehyde into the arcuate nucleus of the hypothalamus induce motor activity in rats
Elsevier (2009)Aims: The hypothalamic arcuate nucleus (ARH) is one of the brain regions with the highest levels of catalase expression. Acetaldehyde, metabolized from ethanol in the CNS through the actions of catalase, has a role in the ... -
Modulation of ethanol-induced conditioned place preference in mice by 3-amino-1,2,4-triazole and D-penicillamine depends on ethanol dose and number of conditioning trials
Springer (2013)Previous studies have shown that both 3-amino-1,2,4-triazole (AT), which inhibits metabolism of ethanol (EtOH) to acetaldehyde by inhibiting catalase, and D-penicillamine (D-P), an acetaldehyde-sequestering agent, modulate ... -
Modulation of the antioxidant system in citrus under waterlogging and subsequent drainage
Elsevier (2009)Soil flooding induces an impairment of the photosynthetic system that often leads to an accumulation of reactive oxygen species (ROS) in plant tissues. Moreover, flooding release by drainage can cause a sudden oxygen burst ... -
Piecing together the puzzle of acetaldehyde as a neuroactive agent
Elsevier (2012-01)Mainly known for its more famous parent compound, ethanol, acetaldehyde was first studied in the 1940s, but then research interest in this compound waned. However, in the last two decades, research on acetaldehyde has seen ... -
Reduction in Central H2O2 Levels Prevents Voluntary Ethanol Intake in Mice: A Role for the Brain Catalase- H2O2 System in Alcohol Binge Drinking
Wiley (2014-01)Background: Hydrogen peroxide (H2O2) is the cosubstrate used by the enzyme catalase to form Compound I (the catalase-H2O2 system), which is the major pathway for the conversion of ethanol (EtOH) into acetaldehyde in the ... -
The H2O2 scavenger ebselen decreases ethanol-induced locomotor stimulation in mice
Elsevier (2012)Background In the brain, the enzyme catalase by reacting with H2O2 forms Compound I (catalase–H2O2 system), which is the main system of central ethanol metabolism to acetaldehyde. Previous research has demonstrated that ... -
The MAO-A inhibitor clorgyline reduces ethanol-induced locomotion and its volitional intake in mice
Elsevier (2014)Hydrogen peroxide is the co-substrate used by the enzyme catalase to form Compound I (the catalase–H2O2 system), which is the major pathway for the conversion of ethanol (EtOH) into acetaldehyde in the brain. This acetaldehyde ... -
The renaissance of acetaldehyde as a psychoactive compound: decades in the making
Frontiers Media (2014-07-22)As with many events in the history of science, the development of the hypothesis that acetaldehyde is a plausible psychoactive substance with specific central effects (not related to its toxic- ity) has not been either ...