Listar por tema "Angiogenesis"
Mostrando ítems 1-5 de 5
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Inhibition of VEGF Expression in Cancer Cells and Endothelial Cell Differentiation by Synthetic Stilbene Derivatives
Elsevier (2013-06-01)We here report the synthesis of several stilbene derivatives. They show a measurable inhibitory effect on angiogenesis, some of them to a higher degree than resveratrol. Test methods included cell proliferation and tube ... -
Novel multitarget inhibitors with antiangiogenic and immunomodulator properties
Elsevier (2019-03-08)By means of docking studies, seventeen compounds T.1-T17 have been designed and evaluated as multitarget inhibitors of VEGFR-2 and PD-L1 proteins in order to overcome resistance phenomena offered by cancer. All these ... -
Síntesis y evaluación biológica de análogos de colchicina
Universitat Jaume I (2017-02-03)Esta Tesis doctoral titulada "Síntesis y evaluación biológica de análogos de colchicina" se enmarca en el campo de la química médica. El objetivo principal es la síntesis de una serie de análogos de colchicina y su posterior ... -
Synthesis and biological evaluation as antiangiogenic agents of ureas derived from 3′-aminocombretastatin A-4
Elsevier (2019-01-15)Twenty-six compounds derived from 3′-aminocombretastatin A-4 (AmCA-4) containing a urea fragment mimicking the structure of Sorafenib, have been synthesized and evaluated as antiangiogenic compounds. Antiproliferative ... -
Synthesis and cytotoxic evaluation of carbamates and ureas derived from styrylanilines
Universitat Jaume I (2017-03-14)Este trabajo forma parte de proyecto relacionado con el diseño, síntesis y evaluación biológica de agentes anticancerígenos. El grupo de síntesis Orgánica de la UJI se centra en la búsqueda de moléculas que puedan inhibir ...