• openAccess   Synthesis and Antiproliferative Activity of 3 and 7-Styrylcoumarins 

      Herrera-R, Angie; Castrillón, Wilson; Otero, Elver; Ruiz, Esneyder; Carda, Miguel; Agut, Raúl; Naranjo Preciado, Tonny; Moreno, Gustavo; Maldonado, María Elena; Cardona Galeano, Wilson Isidro Springer Verlag (2018)
      A series of styrylcoumarins were obtained via Mizoroki-Heck reactions between 3-bromo-4-methyl7-(octyloxy)-2H-chromen-2-one or 2-oxo-2H-chromen-7-yl trifluoromethanesulfonate and functionalized styrenes. The structures ...
    • closedAccess   Synthesis and antiprotozoal activity of furanchalcone–quinoline, furanchalcone–chromone and furanchalcone–imidazole hybrids 

      García, Elisa; Coa, Juan Carlos; Otero, Elver; Carda, Miguel; Vélez, Iván D.; Robledo, Sara M.; Cardona Galeano, Wilson Isidro Springer Verlag (2018)
      We report herein the synthesis and biological activities (cytotoxicity, leishmanicidal, and trypanocidal) of several furanchalcone–quinoline, furanchalcone–chromone, and furanchalcone–imidazole hybrids. The synthesized ...
    • openAccess   Synthesis and leishmanicidal activity of cinnamic acid esters: structure–activity relationship 

      Otero, Elver; Robledo, Sara M.; Diaz-Oltra, Santiago; Carda, Miguel; Muñoz, Diana; Paños Pérez, Julián; Vélez, Iván D.; Cardona Galeano, Wilson Isidro Springer (2014)
      Several cinnamic acid esters were obtained via Fischer esterification of cinnamic acids derivatives with aliphatic alcohols. Structures of the products were elucidated by spectroscopic analysis. The synthesized compounds ...
    • openAccess   Synthesis, Leishmanicidal and Cytotoxic Activity of Triclosan-Chalcone, Triclosan-Chromone and Triclosan-Coumarin Hybrids 

      Otero, Elver; Vergara, Sebastián; Robledo, Sara M.; Cardona Galeano, Wilson Isidro; Carda, Miguel; Vélez, Iván D.; Rojas, Carlos; Otálvaro, Felipe (MDPI) Digital Publishing Institute (2014)
      Twelve hybrids derived from triclosan were obtained via Williamson etherification of O-triclosan alkyl bromide plus chalcone and O-coumarin or O-chromone alkyl bromide plus triclosan, respectively. Structures of the products ...
    • openAccess   Triclosan-caffeic acid hybrids: Synthesis, leishmanicidal, trypanocidal and cytotoxic activities 

      Otero, Elver; García, Elisa; Palacios, Génesis; Yepes, Lina M.; Carda, Miguel; Agut, Raúl; Vélez, Iván D.; Cardona Galeano, Wilson Isidro; Robledo, Sara M. Elsevier (2017-09-29)
      The synthesis, cytotoxicity, anti-leishmanial and anti-trypanosomal activities of twelve triclosan-caffeic acid hybrids are described herein. The structure of the synthesized products was elucidated by a com- bination ...