• openAccess   Efficacy of Self-guided Internet-Based Cognitive Behavioral Therapy in the Treatment of Depressive Symptoms: A Meta-analysis of Individual Participant Data 

      Karyotaki, Eirini; Riper, Heleen; twisk, jos; Hoogendoorn, Adriaan; Kleiboer, A.; Mira, Adriana; Mackinnon, Andrew; Meyer, B.; Botella, Cristina; Littlewood, Elizabeth; Andersson, Gerhard; Christensen, Helen; Klein, Jan P.; Schröder, Johanna; Bretón-López, Juana; Scheider, Justine; Griffiths, K.; Farrer, Louise; Huibers, M. J. H.; Phillips, Rachel; Gilbody, Simon; Moritz, Steffen; Berger, Thomas; pop, victor; Spek, Viola; Cuijpers, Pim American Medical Association (2017-02)
      - Importance: Self-guided internet-based cognitive behavioral therapy (iCBT) has the potential to increase access and availability of evidence-based therapy and reduce the cost of depression treatment. - Objectives: ...
    • openAccess   Is self-guided internet-based cognitive behavioural therapy (iCBT) harmful? An individual participant data meta-analysis 

      Karyotaki, Eirini; Kemmeren, Lise; Riper, Heleen; Twisk, Jos; Hoogendoorn, Adriaan; Kleiboer, Annet; Mira, Adriana; Mackinnon, Andrew; Meyer, Björn; Botella, Cristina; Littlewood, Elizabeth; Andersson, Gerhard; Christensen, Helen; Klein, Jan P.; Schröder, Johanna; Bretón-López, Juana; Scheider, Justine; Griffiths, Kathy; Farrer, Louise; Huibers, Marcus J. H.; Phillips, Rachel; Gilbody, Simon; Moritz, Steffen; Berger, Thomas; Pop, Victor; Spek, Viola; Cuijpers, Pim Cambridge University Press (2018)
      Background. Little is known about potential harmful effects as a consequence of self-guided internet-based cognitive behaviour therapy (iCBT), such as symptom deterioration rates. Thus, safety concerns remain and hamper ...
    • openAccess   Predictors of treatment dropout in self-guided web-based interventions for depression: an ‘individual patient data’ meta-analysis 

      Karyotaki, Eirini; Kleiboer, A.; Smit, F.; Turner, D. T.; Mira, Adriana; Andersson, Gerhard; Berger, Thomas; Botella, Cristina; Bretón-López, Juana; Carlbring, Per; Christensen, Helen; De Graaf, E.; Griffiths, K.; Donker, T.; Farrer, Louise; Huibers, M. J. H.; Lenndin, J.; Mackinnon, Andrew; Meyer, B.; Moritz, S.; Riper, H.; Spek, V.; Vernmark, K.; Cuijpers, Pim Cambridge University Press (2015)
      Background. It is well known that web-based interventions can be effective treatments for depression. However, dropout rates in web-based interventions are typically high, especially in self-guided web-based interventions. ...