Listar por autoría "d52476de-bb49-4150-a2a1-6f126670e765"

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    • closedAccess   Effects on tubulin polymerization and down-regulation of c-Myc, hTERT and VEGF genes by colchicine haloacetyl and haloaroyl derivatives 

      Marzo Mas, Ana; Falomir, Eva; Murga, Juan; Carda, Miguel; Marco, J. Alberto Elsevier (2018-04-25)
      Several colchicine analogues in which the N-acetyl residue has been replaced by haloacetyl, cyclohexylacetyl, phenylacetyl and various aroyl moieties have been synthesized. The cytotoxic activities of the synthesized ...

    • openAccess   Interactions of long-chain homologues of colchicine with tubulin 

      Marzo Mas, Ana; Barbier, Pascale; Breuzard, Gilles; Allegro, Diane; Falomir, Eva; Murga, Juan; Carda, Miguel; Peyrot, Vincent; Marco, J. Alberto Elsevier (2017-01)
      Several colchicine analogues in which the N-acetyl residue has been replaced by aliphatic, straight-chain acyl moieties, have been synthesized. These compounds show high cytotoxic activity at the nanomolar level against ...

    • openAccess   N-alpha-Aminoacyl Colchicines as Promising Anticancer Agents 

      Marzo Mas, Ana; Conesa Milián, Laura; Noppen, Sam; Liekens, Sandra; Falomir, Eva; Murga, Juan; Carda, Miguel; Marco, J. Alberto Bentham Science Publishers (2020-12-29)
      Background: In the last years, many efforts have been made to find colchicine derivatives with reduced toxicity. Additionally, the deregulation of amino acid uptake by cancer cells provides an opportunity to improve ...

    • openAccess   Pregúntate, indaga y a la vez trabaja algunas competencias básicas 

      Marzo Mas, Ana; Monferrer Pons, Llorenç Universidad de Cádiz (2015-01)
      En el presente trabajo se describe una experiencia educativa con alumnos de tercer curso de Educación Secundaria Obligatoria, centrada en los contenidos de “La formulación química inorgánica”. Desde una pregunta o desde ...

    • closedAccess   Use of micellar liquid chromatography for rapid monitoring of fungicides post harvest applied to citrus wastewater 

      Vives-Peris, Vicente; Marzo Mas, Ana; Roca Genovés, Pascual; Carda-Broch, Samuel; Esteve-Romero, Josep Elsevier (2016)
      A method based on micellar liquid chromatography has been developed to simultaneously monitor four pesticides largely post-harvest applied to citrus: thiabendazole, pyrimethanil, o-phenylphenol and imazalil. Water samples ...