Listar por autoría "99677b2c-4432-41ba-88eb-add597d007eb"

Mostrando ítems 1-8 de 8

    • openAccess   Ceria nanoparticles with rhodamine B as a powerful theranostic agent against intracellular oxidative stress 

      Apostolova, Nadezda; Rovira Llopis, Susana; Baldoví, Herme G.; Navalón, Sergio; Asiri, Abdullah M.; Víctor, Víctor M.; García, Hermenegildo; Herance, Jose Raul Royal Society of Chemistry (2015-09)
      Ceria nanoparticles with rhodamine B groups covalently attached on their surface (RhB-CeNPs) were successfully prepared to simultaneously exhibit antioxidant activity and the ability to detect oxidant species. In order to ...

    • closedAccess   ER stress in human hepatic cells treated with Efavirenz: Mitochondria again 

      Apostolova, Nadezda; Gómez Sucerquia, Leysa J.; Alegre, Fernando; Funes, Haryes A.; Víctor, Víctor M.; Barrachina Sancho, María Dolores; Blas García, Ana; Esplugues Mota, Juan V. Elsevier (2013-10)
      Background & Aims ER stress is associated with a growing number of liver diseases, including drug-induced hepatotoxicity. The non-nucleoside analogue reverse transcriptase inhibitor Efavirenz, a cornerstone of the ...

    • closedAccess   Is Glycemic Control Modulating Endoplasmic Reticulum Stress in Leukocytes of Type 2 Diabetic Patients? 

      Rovira Llopis, Susana; Bañuls, Celia; Apostolova, Nadezda; Morillas, Carlos; Hernández Mijares, Antonio; Rocha, Milagros; Víctor, Víctor M. Mary Ann Liebert Inc. (2014-10-06)
      Oxidative and endoplasmic reticulum (ER) stress is related to type 2 diabetes (T2D), but the influence of glycemic control on these parameters and its relationship with leukocyte-endothelial interactions is not known. In ...

    • closedAccess   Mitochondrial (dys)function-a factor underlying the variability of EFV-induced hepatoxicity? 

      Polo, Míriam; Alegre, Fernando; Funes, Haryes A.; Blas García, Ana; Víctor, Víctor M.; Esplugues Mota, Juan V.; Apostolova, Nadezda Wiley (2015-01-08)
      Background and PurposeThe non-nucleoside analogue reverse transcriptase inhibitor efavirenz is associated with hepatic toxicity and metabolic disturbances. Although the mechanisms involved are not clear, recent evidence ...

    • closedAccess   Molecular Strategies for Targeting Antioxidants to Mitochondria: Therapeutic Implications 

      Apostolova, Nadezda; Víctor, Víctor M. Mary Ann Liebert (2015-03-10)
      Mitochondrial function and specifically its implication in cellular redox/oxidative balance is fundamental in controlling the life and death of cells, and has been implicated in a wide range of human pathologies. In this ...

    • closedAccess   Obesity impairs leukocyte‐endothelium cell interactions and oxidative stress in humans 

      López Doménech, Sandra; Bañuls, Celia; Díaz Morales, Noelia; Escribano López, Irene; Morillas, Carlos; Veses, Silvia; Orden, Samuel; Álvarez, Ángeles; Víctor, Víctor M.; Hernández Mijares, Antonio; Rocha, Milagros Wiley (2018-08)
      Background:To evaluate the relationship between leukocyte‐endothelial cellinteractions and oxidative stress parameters in non‐diabetic patients with differentgrades of obesity.Material and methods:For this cross‐sectional ...

    • openAccess   Perspectives and Potential Applications of Mitochondria-Targeted Antioxidants in Cardiometabolic Diseases and Type 2 Diabetes 

      Rocha, Milagros; Apostolova, Nadezda; Herance, Jose Raul; Rovira Llopis, Susana; Hernández Mijares, Antonio; Víctor, Víctor M. John Wiley & Sons (2013)
      There is abundant evidence to suggest that mitochondrial dysfunction is a main cause of insulin resistance and related cardiometabolic comorbidities. On the other hand, insulin resistance is one of the main characteristics ...

    • closedAccess   The purine analogues abacavir and didanosine increase acetaminophen-induced hepatotoxicity by enhancing mitochondrial dysfunction 

      Blas García, Ana; Martí Rodrigo, Alberto; Víctor, Víctor M.; Polo, Míriam; Alegre, Fernando; Funes, Haryes A.; Apostolova, Nadezda; Esplugues Mota, Juan V. Oxford University Press (2016-01-07)
      Background NRTIs are essential components of HIV therapy with well-documented, long-term mitochondrial toxicity in hepatic cells, but whose acute effects on mitochondria are unclear. As acetaminophen-induced hepatotoxicity ...