Listar por autoría "871305b8-9d82-4389-9f69-9ba8dae22d1b"
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Cytotoxic, antiangiogenic and antitelomerase activity of glucosyl- and acyl- resveratrol prodrugs and resveratrol sulfate metabolites
Falomir, Eva; Lucas, Ricardo; Peñalver, Pablo; Martí-Centelles, Rosa; Dupont, Alexia; Zafra Gómez, Alberto; Carda, Miguel; Morales, Juan C. (2016-06)Resveratrol (RES) is a natural polyphenol with relevant and varied biological activity. However, its low bioavailability and rapid metabolism to its glucuronate and sulfate conjugates has opened a debate on the mechanisms ... -
Synthesis, Binding Properties, and Differences in Cell Uptake of G-Quadruplex Ligands Based on Carbohydrate Naphthalene Diimide Conjugates
Arevalo-Ruiz, Matilde; Doria, Filippo; Belmonte Reche, Efres; De Rache, Aurore; Campos-Salinas, Jenny; Lucas, Ricardo; Falomir, Eva; Carda, Miguel; Pérez-Victoria, José María; Mergny, Jean-Louis Wiley (2017-02-10)The G-quadruplexes (G4s) are currently being explored as therapeutic targets in cancer and other pathologies. Six carbohydrate naphthalene diimide conjugates (carb-NDIs) have been synthesized as G4 ligands to investigate ...