Listar por autoría "760320c7-c681-43b4-ba12-a0b57a32337b"

Mostrando ítems 1-7 de 7

    • closedAccess   Chronic Cocaine Effects in Retinal Metabolism and Electrophysiology: Treatment with Topiramate 

      Sánchez-Villarejo, María V.; López-Pedrajas, Rosa; Sánchez Vallejo, Violeta; Genovés, José M.; Muriach Saurí, María; Barcia, Jorge M; Romero, Francisco J. Informa Healthcare (2014)
      Purpose: Cocaine abuse is a major public health problem with multiple-related complications. Indeed, cocaine can affect almost every organ of the human body, but little is known about its effects on the visual system. The ...

    • openAccess   Cocaine promotes oxidative stress and microglial-macrophage activation in rat cerebellum 

      López-Pedrajas, Rosa; Ramírez Lamelas, Dolores T.; Muriach, Borja; Sánchez-Villarejo, María V.; Almansa, Inmaculada; Vidal Gil, Lorena; Romero, Francisco J.; Barcia, Jorge M; Muriach Saurí, María Frontiers Media (2015)
      Different mechanisms have been suggested for cocaine neurotoxicity, including oxidative stress alterations. Nuclear factor kappa B (NF-κB), considered a sensor of oxidative stress and inflammation, is involved in drug ...

    • openAccess   Diabetes and the brain: oxidative stress, inflammation, and autophagy 

      Muriach Saurí, María; Flores-Bellver, Miguel; Romero, Francisco J.; Barcia, Jorge M Hindawi Publishing Corporation (2014)
      Diabetes mellitus is a common metabolic disorder associated with chronic complications including a state of mild to moderate cognitive impairment, in particular psychomotor slowing and reduced mental flexibility, not ...

    • openAccess   Is There A Role for Abscisic Acid, A Proven Anti-Inflammatory Agent, in the Treatment of Ischemic Retinopathies? 

      Baliño, Pablo; Gomez-Cadenas, Aurelio; López Malo, Daniel; Romero, Francisco J.; Muriach, Maria MDPI (2019)
      Ischemic retinopathies (IRs) are the main cause of severe visual impairment and sight loss, and are characterized by loss of blood vessels, accompanied by hypoxia, and neovascularization. Actual therapies, based on ...

    • openAccess   Matching Diabetes and Alcoholism: Oxidative Stress, Inflammation, and Neurogenesis Are Commonly Involved 

      Barcia, Jorge M; Flores-Bellver, Miguel; Muriach Saurí, María; Sancho Pelluz, Francisco Javier; Lopez-Malo, Daniel; Urdaneta, Alba C.; Martinez-Gil, Natalia; Atienzar-Aroca, Sandra; Romero, Francisco J. Hindawi Publishing Corporation (2014)
      Diabetes and alcohol misuse are two of the major challenges in health systems worldwide. These two diseases finally affect several organs and systems including the central nervous system. Hippocampus is one of the most ...

    • openAccess   Naltrexone Reverses Ethanol-Induced Rat Hippocampal and Serum Oxidative Damage 

      Almansa, Inmaculada; Barcia, Jorge M; López-Pedrajas, Rosa; Muriach, Maria; Miranda, María; Romero, Francisco J. Hindawi Publishing Corporation (2013)
      Naltrexone, an antagonist of 𝜇�-opioid receptors, is clinically used as adjuvant therapy of alcohol dishabituation. The aim of the present work was to test the effect of 1 mg/kg body weight of naltrexone to revert oxidative ...

    • openAccess   Serum Malondialdehyde Concentration and Glutathione Peroxidase Activity in a Longitudinal Study of Gestational Diabetes 

      Arribas, Luis; Almansa, Inmaculada; Miranda, M.; Muriach Saurí, María; Romero, Francisco J.; Villar, Vincent M. Public Library of Science (2016)
      Aims The main goal of this study was to evaluate the presence of oxidative damage and to quantify its level in gestational diabetes. Methods Thirty-six healthy women and thirty-six women with gestational diabetes ...