• openAccess   On the relationship between folding and chemical landscapes in enzyme catalysis 

      Roca, Maite; Messer, Benjamin; Hilvert, Donald; Warshel, Arieh National Academy of Sciences (2008-09-16)
      Elucidating the relationship between the free energy landscape of enzymes and their catalytic power has been one of the challenges of modern enzymology. The present work explores this issue by using a simplified folding ...