Listar por autoría "2879f9df-1baa-459d-8d05-34ec458a17e9"
Mostrando ítems 1-8 de 8
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An anti-interleukin-2 receptor drug attenuates thelper 1 lymphocytes-mediated inflammation in an acute model of endotoxin-induced uveitis
Mérida, S.; Sancho Tello, M.; Navea, A.; Almansa, Inmaculada; Muriach Saurí, María; Bosch Morell, F. Public Library of Science (2014)The aim of the present study was to evaluate the anti-inflammatory efficacy of Daclizumab, an anti-interleukin-2 receptor drug, in an experimental uveitis model upon a subcutaneous injection of lipopolysaccharide into ... -
Chronic Cocaine Effects in Retinal Metabolism and Electrophysiology: Treatment with Topiramate
Sánchez-Villarejo, María V.; López-Pedrajas, Rosa; Sánchez Vallejo, Violeta; Genovés, José M.; Muriach Saurí, María; Barcia, Jorge M; Romero, Francisco J. Informa Healthcare (2014)Purpose: Cocaine abuse is a major public health problem with multiple-related complications. Indeed, cocaine can affect almost every organ of the human body, but little is known about its effects on the visual system. The ... -
Cocaine promotes oxidative stress and microglial-macrophage activation in rat cerebellum
López-Pedrajas, Rosa; Ramírez Lamelas, Dolores T.; Muriach, Borja; Sánchez-Villarejo, María V.; Almansa, Inmaculada; Vidal Gil, Lorena; Romero, Francisco J.; Barcia, Jorge M; Muriach Saurí, María Frontiers Media (2015)Different mechanisms have been suggested for cocaine neurotoxicity, including oxidative stress alterations. Nuclear factor kappa B (NF-κB), considered a sensor of oxidative stress and inflammation, is involved in drug ... -
Diabetes and the brain: oxidative stress, inflammation, and autophagy
Muriach Saurí, María; Flores-Bellver, Miguel; Romero, Francisco J.; Barcia, Jorge M Hindawi Publishing Corporation (2014)Diabetes mellitus is a common metabolic disorder associated with chronic complications including a state of mild to moderate cognitive impairment, in particular psychomotor slowing and reduced mental flexibility, not ... -
Differential hippocampal response to chronic alcohol consumption of young adult and mature adult rats
Barcia, Jorge M; Sánchez-Villarejo, María V.; Almansa, Inmaculada; López-Pedrajas, Rosa; Muriach Saurí, María; Romero Gómez, Francisco Javier Oxford University Press (2012-05)AIMS Early ethanol consumption could be a risk factor for young brain integrity and its maturation, and also for the development of addictive behaviors in adulthood. Neuronal nitric oxide synthase (nNOS) expressing neurons ... -
Lipoic acid lessens Th1-mediated inflammation in lipopolysaccharide-induced uveitis reducing selectively Th1 lymphocytes-related cytokines release
Mérida, S.; Sancho Tello, M.; Muriach Saurí, María; Miranda, M.; Navea, A.; Bosch Morell, F. Informa HealthCare (2013-08)Infl ammation results in the production of free radicals. We evaluated the anti-infl ammatory and antioxidant capacity of lipoic acid in an experimental uveitis model upon a subcutaneous injection of endotoxin into Lewis ... -
Matching Diabetes and Alcoholism: Oxidative Stress, Inflammation, and Neurogenesis Are Commonly Involved
Barcia, Jorge M; Flores-Bellver, Miguel; Muriach Saurí, María; Sancho Pelluz, Francisco Javier; Lopez-Malo, Daniel; Urdaneta, Alba C.; Martinez-Gil, Natalia; Atienzar-Aroca, Sandra; Romero, Francisco J. Hindawi Publishing Corporation (2014)Diabetes and alcohol misuse are two of the major challenges in health systems worldwide. These two diseases finally affect several organs and systems including the central nervous system. Hippocampus is one of the most ... -
Serum Malondialdehyde Concentration and Glutathione Peroxidase Activity in a Longitudinal Study of Gestational Diabetes
Arribas, Luis; Almansa, Inmaculada; Miranda, M.; Muriach Saurí, María; Romero, Francisco J.; Villar, Vincent M. Public Library of Science (2016)Aims The main goal of this study was to evaluate the presence of oxidative damage and to quantify its level in gestational diabetes. Methods Thirty-six healthy women and thirty-six women with gestational diabetes ...