2024-03-29T10:00:27Zhttps://repositori.uji.es/oai/requestoai:repositori.uji.es:10234/738862021-05-10T07:46:04Zcom_10234_7053com_10234_9col_10234_8639
00925njm 22002777a 4500
dc
Ribés Vidal, Celia
author
Falomir, Eva
author
Carda, Miguel
author
Marco, J. Alberto
author
2008
A short, stereoselective synthesis of the naturally occurring pyrrolidine radicamine B is reported. Garner′s (R)-aldehyde, prepared from d-serine, was the chiral starting material. The pyrrolidine ring was stereoselectively created in a very efficient way through a five-step, one-pot transformation. In addition, an intermediate of this synthesis was transformed into an intermediate of a previously published synthesis of the potent α-glucosidase inhibitor nectrisine.
Journal of Organic Chemistry, 73, 19, p. 7779–7782
0022-3263
http://hdl.handle.net/10234/73886
http://dx.doi.org/10.1021/jo8012989
Aldehydes
Stereochemistry
Chemical reactions
Organic compounds
Short, Stereoselective Synthesis of the Naturally Occurring Pyrrolidine Radicamine B and a Formal Synthesis of Nectrisine