2024-03-28T08:26:03Zhttps://repositori.uji.es/oai/requestoai:repositori.uji.es:10234/1748572023-09-26T12:49:50Zcom_10234_7053com_10234_9col_10234_8639
00925njm 22002777a 4500
dc
Felip-León, Carles
author
Cejudo Marín, Rocío
author
Peris, Mireia
author
Galindo, Francisco
author
Miravet, Juan
author
2017
A low molecular weight gelator with a fluorescent 1,8-
naphthalimide unit forms micro- and nanoparticles in aqueous media. Slow
addition of a DMSO solution of the gelator into water affords either a selfassembled
fibrillar network, sheaf-like microparticles, or nanoparticles
depending to the concentration used in the experiment. The micro- and
nanoparticles were characterized by dynamic light scattering (DLS), electron
microscopy, and fluorescence measurements. In an initial assay of particle
loading, Rose Bengal and Rhodamine 123 were shown to be incorporated in
the particles. Light-promoted singlet oxygen generation capabilities of Rose
Bengal were modulated by its incorporation in the particles. Additionally, the
particles were found to promote the transport of Rhodamine 123 into human
lung carcinoma live cells. These results indicate that nanoparticles arising from
low molecular weight gelators may represent a new type of nanocarriers, being
a potential alternative to polymeric nanogels used in nanomedicine.
0743-7463
1520-5827
http://hdl.handle.net/10234/174857
https://doi.org/10.1021/acs.langmuir.7b02440
Sizing Down a Supramolecular Gel into Micro- and Nanoparticles